Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896989932> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2896989932 endingPage "140" @default.
- W2896989932 startingPage "129" @default.
- W2896989932 abstract "Esophageal cancer (EC) is one of the deadliest malignancies worldwide. Esophageal squamous cell carcinoma (ESCC) constitutes the most common type of EC in Asian countries. Despite advanced surgical techniques, 5-year survival of the affected patients is very low. Therefore, identification of genetic factors and cellular regulatory pathways, including microRNAs (miRNAs), in esophageal carcinogenesis is necessary for early detection. MiRNAs are a class of small non-coding RNA about 18-24 nucleotides in length that negatively regulate gene expression. Deregulation of miRNAs was shown to have a crucial role in the pathways underlying tumorigenesis and tumor progression. Evidence indicates that aberrant expression pattern of miR-100 is associated with pathogenesis of ESCC. The function and expression pattern of miR-100 in ESCC are controversial and its effects in tumor progression has not been fully elucidated. A better understanding of molecular procedures mediated by miR-100 in carcinogenesis, may lead to the opportunity of exploring potential miR-100 based therapeutic applications. In this review, we provide an overview of miR-100, including its important regulation pathways and target genes involved in the development of cancers, emphasizing on its potential role in ESCC." @default.
- W2896989932 created "2018-10-26" @default.
- W2896989932 creator A5006767210 @default.
- W2896989932 creator A5031908085 @default.
- W2896989932 creator A5064272520 @default.
- W2896989932 date "2018-10-07" @default.
- W2896989932 modified "2023-09-26" @default.
- W2896989932 title "Tumor Suppression or Oncogenic Role of miR-100 in Cancer; Implications for Esophageal Cancer" @default.
- W2896989932 hasPublicationYear "2018" @default.
- W2896989932 type Work @default.
- W2896989932 sameAs 2896989932 @default.
- W2896989932 citedByCount "0" @default.
- W2896989932 crossrefType "journal-article" @default.
- W2896989932 hasAuthorship W2896989932A5006767210 @default.
- W2896989932 hasAuthorship W2896989932A5031908085 @default.
- W2896989932 hasAuthorship W2896989932A5064272520 @default.
- W2896989932 hasConcept C104317684 @default.
- W2896989932 hasConcept C121608353 @default.
- W2896989932 hasConcept C145059251 @default.
- W2896989932 hasConcept C2779256057 @default.
- W2896989932 hasConcept C2779742542 @default.
- W2896989932 hasConcept C502942594 @default.
- W2896989932 hasConcept C54355233 @default.
- W2896989932 hasConcept C555283112 @default.
- W2896989932 hasConcept C60644358 @default.
- W2896989932 hasConcept C86803240 @default.
- W2896989932 hasConceptScore W2896989932C104317684 @default.
- W2896989932 hasConceptScore W2896989932C121608353 @default.
- W2896989932 hasConceptScore W2896989932C145059251 @default.
- W2896989932 hasConceptScore W2896989932C2779256057 @default.
- W2896989932 hasConceptScore W2896989932C2779742542 @default.
- W2896989932 hasConceptScore W2896989932C502942594 @default.
- W2896989932 hasConceptScore W2896989932C54355233 @default.
- W2896989932 hasConceptScore W2896989932C555283112 @default.
- W2896989932 hasConceptScore W2896989932C60644358 @default.
- W2896989932 hasConceptScore W2896989932C86803240 @default.
- W2896989932 hasIssue "3" @default.
- W2896989932 hasLocation W28969899321 @default.
- W2896989932 hasOpenAccess W2896989932 @default.
- W2896989932 hasPrimaryLocation W28969899321 @default.
- W2896989932 hasRelatedWork W1526266797 @default.
- W2896989932 hasRelatedWork W2138930960 @default.
- W2896989932 hasRelatedWork W2528211056 @default.
- W2896989932 hasRelatedWork W2548902544 @default.
- W2896989932 hasRelatedWork W2727082134 @default.
- W2896989932 hasRelatedWork W2972806461 @default.
- W2896989932 hasRelatedWork W2995978162 @default.
- W2896989932 hasRelatedWork W3008327040 @default.
- W2896989932 hasRelatedWork W3014382501 @default.
- W2896989932 hasRelatedWork W3033076806 @default.
- W2896989932 hasRelatedWork W3041482552 @default.
- W2896989932 hasRelatedWork W3087686865 @default.
- W2896989932 hasRelatedWork W3088718918 @default.
- W2896989932 hasRelatedWork W3092548801 @default.
- W2896989932 hasRelatedWork W3109320761 @default.
- W2896989932 hasRelatedWork W3128301585 @default.
- W2896989932 hasRelatedWork W3129396836 @default.
- W2896989932 hasRelatedWork W3161697875 @default.
- W2896989932 hasRelatedWork W3163237053 @default.
- W2896989932 hasRelatedWork W3196094192 @default.
- W2896989932 hasVolume "23" @default.
- W2896989932 isParatext "false" @default.
- W2896989932 isRetracted "false" @default.
- W2896989932 magId "2896989932" @default.
- W2896989932 workType "article" @default.