Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897000512> ?p ?o ?g. }
- W2897000512 abstract "Toll-like receptors (TLRs) play an important role in immune-surveillance and responses towards pathogenic and non-pathogenic microorganisms. They act as innate immune sensors against endogenous and exogenous danger signals by recognizing the pattern recognition molecules (DAMPs and PAMPs) and drive an adaptive immune response through their signaling pathways, which leads to NF-κB and IRF3 transactivation and induces different inflammatory cytokine genes. TLRs polymorphisms were investigated in various cancer types studies. However, precious studies have reported that the Polymorphisms on TLR1-TLR10 cluster have been associated with increased risk of prostate cancer. However, it has known that TLRs genetic variation is associated with increased the susceptibility to gastric cancer. A same synthetically meta- analysis also confirmed the association of TLRs with increased the gastrointestinal cancer but with decreased prostate cancer risk. Our previous studies have demonstrated a strong link between TLRs polymorphisms and colon cancer and breast cancer in Saudi Arabia population. Similar studies were analyzed with Korean patients with papillary thyroid cancer and their clinic-pathologic features in age matched controls by using direct sequencing. The general objective of this chapter was to investigate the role of different TLRs (i.e., TLR2, TLR4, and TLR6) polymorphisms and their association with cancer development." @default.
- W2897000512 created "2018-10-26" @default.
- W2897000512 creator A5028584917 @default.
- W2897000512 creator A5057758924 @default.
- W2897000512 creator A5060640447 @default.
- W2897000512 creator A5068600705 @default.
- W2897000512 creator A5084869111 @default.
- W2897000512 date "2018-10-17" @default.
- W2897000512 modified "2023-09-23" @default.
- W2897000512 title "Toll-Like Receptors Gene Polymorphism and Susceptibility to Cancer Development" @default.
- W2897000512 cites W1166818499 @default.
- W2897000512 cites W135825401 @default.
- W2897000512 cites W1455781541 @default.
- W2897000512 cites W1505434768 @default.
- W2897000512 cites W1508952387 @default.
- W2897000512 cites W1511030747 @default.
- W2897000512 cites W1549149988 @default.
- W2897000512 cites W1772966975 @default.
- W2897000512 cites W1792405584 @default.
- W2897000512 cites W1934712179 @default.
- W2897000512 cites W1943120621 @default.
- W2897000512 cites W1972689531 @default.
- W2897000512 cites W1976208319 @default.
- W2897000512 cites W1979395539 @default.
- W2897000512 cites W1979978699 @default.
- W2897000512 cites W1987108483 @default.
- W2897000512 cites W1995110153 @default.
- W2897000512 cites W1995177733 @default.
- W2897000512 cites W2001669571 @default.
- W2897000512 cites W2006423274 @default.
- W2897000512 cites W2011464013 @default.
- W2897000512 cites W2019628619 @default.
- W2897000512 cites W2025412364 @default.
- W2897000512 cites W2026893251 @default.
- W2897000512 cites W2030611349 @default.
- W2897000512 cites W2036767516 @default.
- W2897000512 cites W2037580272 @default.
- W2897000512 cites W2037623926 @default.
- W2897000512 cites W2038486513 @default.
- W2897000512 cites W2043003819 @default.
- W2897000512 cites W2055072058 @default.
- W2897000512 cites W2059645954 @default.
- W2897000512 cites W2060982768 @default.
- W2897000512 cites W2061217549 @default.
- W2897000512 cites W2066664002 @default.
- W2897000512 cites W2074120439 @default.
- W2897000512 cites W2079379555 @default.
- W2897000512 cites W2079955793 @default.
- W2897000512 cites W2082821194 @default.
- W2897000512 cites W2083935421 @default.
- W2897000512 cites W2087768117 @default.
- W2897000512 cites W2091229884 @default.
- W2897000512 cites W2092531978 @default.
- W2897000512 cites W2093075617 @default.
- W2897000512 cites W2097339934 @default.
- W2897000512 cites W2099803791 @default.
- W2897000512 cites W2101624429 @default.
- W2897000512 cites W2109042013 @default.
- W2897000512 cites W2111619196 @default.
- W2897000512 cites W2114844727 @default.
- W2897000512 cites W2116692899 @default.
- W2897000512 cites W2125099402 @default.
- W2897000512 cites W2133289250 @default.
- W2897000512 cites W2140198099 @default.
- W2897000512 cites W2149465719 @default.
- W2897000512 cites W2150324671 @default.
- W2897000512 cites W2151710088 @default.
- W2897000512 cites W2155891127 @default.
- W2897000512 cites W2157527462 @default.
- W2897000512 cites W2160057355 @default.
- W2897000512 cites W2167051103 @default.
- W2897000512 cites W2175507590 @default.
- W2897000512 cites W2175687902 @default.
- W2897000512 cites W2213473402 @default.
- W2897000512 cites W2243694148 @default.
- W2897000512 cites W2319863749 @default.
- W2897000512 cites W2375082280 @default.
- W2897000512 cites W2397763399 @default.
- W2897000512 cites W2562421369 @default.
- W2897000512 cites W2592172886 @default.
- W2897000512 cites W2750247054 @default.
- W2897000512 cites W2752917247 @default.
- W2897000512 cites W2891383619 @default.
- W2897000512 doi "https://doi.org/10.5772/intechopen.78029" @default.
- W2897000512 hasPublicationYear "2018" @default.
- W2897000512 type Work @default.
- W2897000512 sameAs 2897000512 @default.
- W2897000512 citedByCount "2" @default.
- W2897000512 countsByYear W28970005122020 @default.
- W2897000512 countsByYear W28970005122021 @default.
- W2897000512 crossrefType "book-chapter" @default.
- W2897000512 hasAuthorship W2897000512A5028584917 @default.
- W2897000512 hasAuthorship W2897000512A5057758924 @default.
- W2897000512 hasAuthorship W2897000512A5060640447 @default.
- W2897000512 hasAuthorship W2897000512A5068600705 @default.
- W2897000512 hasAuthorship W2897000512A5084869111 @default.
- W2897000512 hasBestOaLocation W28970005121 @default.
- W2897000512 hasConcept C104317684 @default.
- W2897000512 hasConcept C121608353 @default.
- W2897000512 hasConcept C1292079 @default.