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- W2897027768 abstract "Knowledge of population-level processes is essential to understanding the efficacy of selection operating within a species. However, attempts at estimating effective population sizes (Ne) are particularly challenging in bacteria due to their extremely large census populations sizes, varying rates of recombination and arbitrary species boundaries. In this study, we estimated Ne for 153 species (152 bacteria and one archaeon) defined under a common framework and found that ecological lifestyle and growth rate were major predictors of Ne; and that contrary to theoretical expectations, Ne was unaffected by recombination rate. Additionally, we found that Ne shapes the evolution and diversity of total gene repertoires of prokaryotic species. Together, these results point to a new model of genome architecture evolution in prokaryotes, in which pan-genome sizes, not individual genome sizes, are governed by drift-barrier evolution." @default.
- W2897027768 created "2018-10-26" @default.
- W2897027768 creator A5033055063 @default.
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- W2897027768 date "2018-10-12" @default.
- W2897027768 modified "2023-10-18" @default.
- W2897027768 title "Factors driving effective population size and pan-genome evolution in bacteria" @default.
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- W2897027768 doi "https://doi.org/10.1186/s12862-018-1272-4" @default.
- W2897027768 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6186134" @default.
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