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• W2897033664 abstract "Abstract Inositol-stabilized arginine silicate, otherwise referred to as arginine silicate inositol (ASI), is a novel bioavailable source of arginine, silicon, and inositol providing multiple health benefits. ASI is comprises a bonded arginine–silicate complex, stabilized by inositol. It has been affirmed as generally recognized as safe and is marketed in the United States after Food and Drug Administration New Dietary Ingredient Notification under the tradename Nitrosigine. It starts to work within 15 min of ingesting and significantly increases arginine levels for up to 6 h (Kalman et al., 2015). ASI has been shown to provide benefits in several populations, including those involved in athletic fitness. A study of healthy active males, supplementing 1500 mg of ASI daily for 4 days, reported significantly increased preworkout energy levels and increased muscle hyperemia or “pump” after exercise (Rood-Ojalvo et al., 2015). There is also evidence to support its role as a sports nutrition ingredient by improving cognitive function and focus before exercise (Kalman et al., 2016) and muscle recovery after exercise (Rood-Ojalvo et al., 2015). The effects of arginine and silicon on joint health and connective tissue metabolism in mammals are well documented, and the ASI complex has been shown to benefit bone and vascular health (Russell, 2005). Related benefits of the ASI complex include a report of decreased periodontal destruction in rats with induced periodontitis (Dundar et al., 2016) and decreased wound healing time in rats when ASI was applied topically (Durmus et al., 2017). The major objective of this chapter is to provide an overview of the research on the efficacy and safety of ASI with focus on the sports nutrition market." @default.
• W2897033664 created "2018-10-26" @default.
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• W2897033664 date "2019-01-01" @default.
• W2897033664 modified "2023-10-16" @default.
• W2897033664 title "Inositol-Stabilized Arginine Silicate" @default.
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• W2897033664 doi "https://doi.org/10.1016/b978-0-12-813922-6.00059-x" @default.
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