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• W2897035618 abstract "In order to realize the multi-analyte assays for physiological molecules and environmental contaminants, a bi-enzyme biosensor based on horseradish peroxidase (HRP)-catalyzed noradrenalin (NA) polymerization in the presence of H2O2 was fabricated for the first time and utilized in immobilizing HRP and glucose oxidase (GOx) simultaneously. The resultant bi-enzyme modified electrode was demonstrated to be efficient in monitoring multi-analyte (H2O2, Cr(III), glucose, and Cr(VI)). It was shown that the prepared PNA-HRP-GOx/Pt electrode exhibits a sensitivity (S) high up to 628.4 μA mM−1 cm−2 in the linear range (LR) of 0.50 μM ~ 0.42 mM and a S of 208.9 μA mM−1 cm−2 in the LR of 0.42 mM~3.5 mM in glucose sensing, with a limit of detection (LOD) of 0.08 μM observed; in Cr(VI) sensing a LOD of 0.20 nM and a LR of 0.50 ~ 6.0 nM were obtained. With the addition of polyaniline (PANI), the resultant PNA-HRP-GOx/PANI/Pt electrode potentiostated at − 0.20 V responded linearly to H2O2 concentration in 0.05 ~ 30.2 mM range, with linearly responses to Cr(III) concentration in the LR of 0.01 ~ 3.8 μM. Hence, amperometric biosensors with high S, low LOD and good anti-interference ability for detection of glucose, H2O2 and heavy metal ions (Cr(III) and Cr(VI)) were developed." @default.
• W2897035618 created "2018-10-26" @default.
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• W2897035618 date "2019-03-01" @default.
• W2897035618 modified "2023-10-02" @default.
• W2897035618 title "Poly(noradrenalin) based bi-enzyme biosensor for ultrasensitive multi-analyte determination" @default.
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• W2897035618 doi "https://doi.org/10.1016/j.talanta.2018.10.055" @default.
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