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- W2897052485 abstract "The aim of this study is to assess the accuracy of the diagnosis of hydatidiform mole with transvaginal ultrasound (TVS) prior to evacuation and histological examination of the removed products. A retrospective analysis was performed of all partial and complete molar pregnancies that were diagnosed at Nepean Hospital early pregnancy unit between 2011 and Feb 2017, both sonographically and histologically. A total of 7,193 women were seen in the Early Pregnancy Unit during that time. 40/7193 (0.01%) had gestational trophoblastic disease (GTD) histologically. The true sensitivity and PPV was then calculated for ultrasound diagnosis of hydatidiform mole from those that had been proven histologically. A total of 43 patients were included in the study. Of the 43 cases, 40 (0.01%) were confirmed to have GTD. Twenty-nine (72.5%) were suspected to have GTD on TVS prior to evacuation and examination of the removed products. Histologically, 25 (62.5%) had a complete molar pregnancy (CMP). Eighteen (72%) were suspected on TVS. Fifteen were histologically confirmed to have partial molar pregnancies (PMP). Six (4%) were suspected on TVS preoperatively. The overall sensitivity was 59% with a PPV of 90% for ultrasound diagnosis of a molar pregnancy. The CMP sensitivity was 72% and PPV 97.3% and for PMP 37% and 67% respectively. Ultrasonography is more accurate in diagnosing CMP than PMP. The overall ultrasound sensitivity in our unit is 59% for preoperative diagnosis. However, histology is still the gold standard for the diagnosis of hydatidiform mole. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
- W2897052485 created "2018-10-26" @default.
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- W2897052485 date "2018-10-01" @default.
- W2897052485 modified "2023-10-18" @default.
- W2897052485 title "OP16.08: The proportion of women with a histological diagnosis of molar pregnancy who are diagnosed with ultrasound prior to uterine evacuation" @default.
- W2897052485 doi "https://doi.org/10.1002/uog.19541" @default.
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