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• W2897056944 endingPage "366" @default.
• W2897056944 startingPage "361" @default.
• W2897056944 abstract "Progress in our understanding of the central genes, pathways, and mechanisms in the pathobiology of T-cell acute lymphoblastic leukemia (T-ALL) has identified key drivers of the disease, opening new opportunities for therapy. Drugs targeting highly prevalent genetic alterations in NOTCH1 and CDKN2A are being explored, and multiple other targets with readily available therapeutic agents, and immunotherapies are being investigated. The molecular basis of T-ALL is reviewed here and potential targets and therapeutic targets discussed." @default.
• W2897056944 created "2018-10-26" @default.
• W2897056944 creator A5020549289 @default.
• W2897056944 date "2018-12-01" @default.
• W2897056944 modified "2023-10-02" @default.
• W2897056944 title "Can one target T-cell ALL?" @default.
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• W2897056944 doi "https://doi.org/10.1016/j.beha.2018.10.001" @default.
• W2897056944 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6294319" @default.
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• W2897056944 hasPublicationYear "2018" @default.
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