FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897059652> ?p ?o ?g. }

• W2897059652 endingPage "354" @default.
• W2897059652 startingPage "344" @default.
• W2897059652 abstract "MALDI fingerprinting was first described two decades ago as a technique to identify microbial cell lines. Microbial fingerprinting has since evolved into an automated platform for microorganism identification and classification, which is now routinely used in clinical and environmental sectors. The extension of fingerprinting to mammalian cells has yet to progress partly due to compartmentalization of eukaryotic cells and overall higher cellular complexity. A number of publications on mammalian whole cell fingerprinting suggest that the method could be useful for classification of different cell types, cell states, and monitoring cell differentiation. We report the optimization of MALDI fingerprinting workflow parameters for mammalian cells and its application for differential profiling of mammalian cell lines and two-component cell line mixtures. Murine fallopian tube cells and high-grade ovarian carcinoma cell lines and their mixtures are used as model mammalian cell lines. Two-component cell mixtures serve to determine the method's feasibility for complex biological samples as the ability to detect cancer cells in a mixed cell population. The level of detection of cancer cells in the two-component mixture by principle component analysis (PCA) starts to deteriorate at 5% but with application of a different statistical approach, Wilcoxon rank sum test, the level of detection was determined to be 1%. The ability to differentiate heterogeneous cell mixtures will help further extend whole cell MALDI fingerprinting to complex biological systems. Graphical Abstract." @default.
• W2897059652 created "2018-10-26" @default.
• W2897059652 creator A5024294799 @default.
• W2897059652 creator A5032764121 @default.
• W2897059652 creator A5039917424 @default.
• W2897059652 creator A5040296076 @default.
• W2897059652 creator A5058074901 @default.
• W2897059652 creator A5063822465 @default.
• W2897059652 creator A5068626380 @default.
• W2897059652 creator A5073932070 @default.
• W2897059652 date "2018-10-23" @default.
• W2897059652 modified "2023-09-24" @default.
• W2897059652 title "Whole Cell MALDI Fingerprinting Is a Robust Tool for Differential Profiling of Two-Component Mammalian Cell Mixtures" @default.
• W2897059652 cites W1936066510 @default.
• W2897059652 cites W1969834097 @default.
• W2897059652 cites W1972978214 @default.
• W2897059652 cites W1974279612 @default.
• W2897059652 cites W1980062178 @default.
• W2897059652 cites W1981683447 @default.
• W2897059652 cites W1982148128 @default.
• W2897059652 cites W1986648633 @default.
• W2897059652 cites W1987227393 @default.
• W2897059652 cites W1990107423 @default.
• W2897059652 cites W2001509485 @default.
• W2897059652 cites W2006775149 @default.
• W2897059652 cites W2007567302 @default.
• W2897059652 cites W2014136504 @default.
• W2897059652 cites W2014820375 @default.
• W2897059652 cites W2026927133 @default.
• W2897059652 cites W2037268730 @default.
• W2897059652 cites W2039805990 @default.
• W2897059652 cites W2041626597 @default.
• W2897059652 cites W2045825094 @default.
• W2897059652 cites W2052858711 @default.
• W2897059652 cites W2061554433 @default.
• W2897059652 cites W2062603056 @default.
• W2897059652 cites W2065119049 @default.
• W2897059652 cites W2065488667 @default.
• W2897059652 cites W2066927692 @default.
• W2897059652 cites W2080212641 @default.
• W2897059652 cites W2082375578 @default.
• W2897059652 cites W2087144120 @default.
• W2897059652 cites W2103505892 @default.
• W2897059652 cites W2105690536 @default.
• W2897059652 cites W2115445096 @default.
• W2897059652 cites W2120953279 @default.
• W2897059652 cites W2127073086 @default.
• W2897059652 cites W2143458495 @default.
• W2897059652 cites W2147214095 @default.
• W2897059652 cites W2166860594 @default.
• W2897059652 cites W2171900074 @default.
• W2897059652 cites W2260372776 @default.
• W2897059652 cites W2277901605 @default.
• W2897059652 cites W2298006650 @default.
• W2897059652 cites W2314103994 @default.
• W2897059652 cites W2325765883 @default.
• W2897059652 cites W2337132994 @default.
• W2897059652 cites W2419639724 @default.
• W2897059652 cites W2534227485 @default.
• W2897059652 cites W2566398522 @default.
• W2897059652 cites W2615112694 @default.
• W2897059652 cites W2740456701 @default.
• W2897059652 cites W2744599847 @default.
• W2897059652 cites W2767715277 @default.
• W2897059652 cites W2767989234 @default.
• W2897059652 cites W2781807964 @default.
• W2897059652 cites W2792350258 @default.
• W2897059652 cites W2800416655 @default.
• W2897059652 cites W2805177948 @default.
• W2897059652 doi "https://doi.org/10.1007/s13361-018-2088-6" @default.
• W2897059652 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6347503" @default.
• W2897059652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30353292" @default.
• W2897059652 hasPublicationYear "2018" @default.
• W2897059652 type Work @default.
• W2897059652 sameAs 2897059652 @default.
• W2897059652 citedByCount "9" @default.
• W2897059652 countsByYear W28970596522019 @default.
• W2897059652 countsByYear W28970596522021 @default.
• W2897059652 countsByYear W28970596522022 @default.
• W2897059652 countsByYear W28970596522023 @default.
• W2897059652 crossrefType "journal-article" @default.
• W2897059652 hasAuthorship W2897059652A5024294799 @default.
• W2897059652 hasAuthorship W2897059652A5032764121 @default.
• W2897059652 hasAuthorship W2897059652A5039917424 @default.
• W2897059652 hasAuthorship W2897059652A5040296076 @default.
• W2897059652 hasAuthorship W2897059652A5058074901 @default.
• W2897059652 hasAuthorship W2897059652A5063822465 @default.
• W2897059652 hasAuthorship W2897059652A5068626380 @default.
• W2897059652 hasAuthorship W2897059652A5073932070 @default.
• W2897059652 hasBestOaLocation W28970596522 @default.
• W2897059652 hasConcept C104317684 @default.
• W2897059652 hasConcept C144024400 @default.
• W2897059652 hasConcept C1491633281 @default.
• W2897059652 hasConcept C149923435 @default.
• W2897059652 hasConcept C185592680 @default.
• W2897059652 hasConcept C189014844 @default.
• W2897059652 hasConcept C2908647359 @default.
• W2897059652 hasConcept C46111723 @default.

• next