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• W2897060852 endingPage "1208" @default.
• W2897060852 startingPage "1202" @default.
• W2897060852 abstract "Abstract In this paper, a fluoro‐hydroxylation of gem ‐difluoroalkenes is demonstrated. This protocol uses sequential electrophilic fluorination with Selectfluor and nucleophilic hydroxylation with H 2 18 O, which can be used to prepare 18 O‐labeled α‐CF 3 alcohols from gem ‐difluorostyrenes. The reaction is typically carried out at room temperature within 4 h in good to excellent yields. Other nucleophiles (besides H 2 18 O), such as alcohols, carboxylic acid, acetonitrile and N,N ‐dimethylformamide, are also suitable for this difunctionalization of gem ‐difluoroalkenes." @default.
• W2897060852 created "2018-10-26" @default.
• W2897060852 creator A5005128136 @default.
• W2897060852 creator A5035062255 @default.
• W2897060852 creator A5039045389 @default.
• W2897060852 creator A5047649448 @default.
• W2897060852 creator A5082687032 @default.
• W2897060852 date "2018-10-25" @default.
• W2897060852 modified "2023-10-10" @default.
• W2897060852 title "Fluoro‐Hydroxylation of <i>gem</i>‐Difluoroalkenes: Synthesis of ¹⁸O‐labeled α‐CF₃ Alcohols" @default.
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