Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897069726> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2897069726 endingPage "455" @default.
- W2897069726 startingPage "446" @default.
- W2897069726 abstract "Symptom severity in trichotillomania clinical trials is typically rated using the Massachusetts General Hospital Hair Pulling Scale (MGH-HPS) and the National Institute of Mental Health Trichotillomania Severity Scale (NIMH-TSS). There are no universal definitions of treatment response on these scales. The absence of empirically supported definitions of treatment response hampers advances in trichotillomania treatment.PubMed and CENTRAL databases were searched for trichotillomania clinical trials. A total of 14 studies were identified and 7 provided adequate data to be included in the meta-analysis (n = 270). Meta-DiSc software was employed. The Youden index and distance to corner were used to determine the optimal cut-point. Response was defined by the Clinical Global Impressions Improvement scale score ≤ 2.The optimal cut-points for identifying response on the MGH-HPS was a 35% percent reduction [Youden Index 0.48; distance to corner 0.37] or a seven-point reduction [Youden Index 0.43; distance to corner 0.40]. The optimal cut-points for the NIMH-TSS was a 50% reduction [Youden Index 0.57; distance to corner 0.34] or a six-point reduction [Youden Index 0.53; distance to corner 0.36]. The optimal cut-points were similar when the analysis was confined to only trichotillomania trials involving adult subjects, but the scales appeared to have improved ability to define treatment response when pediatric subjects were excluded.This study provides empirically determined cut-points of treatment response on the MGH-HPS and NIMH-TSS. These data-driven cut-points will benefit future research in trichotillomania by providing definitions of treatment response that can be defined a priori in clinical trials." @default.
- W2897069726 created "2018-10-26" @default.
- W2897069726 creator A5004690387 @default.
- W2897069726 creator A5008981904 @default.
- W2897069726 creator A5011291875 @default.
- W2897069726 creator A5050882868 @default.
- W2897069726 creator A5060512263 @default.
- W2897069726 date "2019-03-01" @default.
- W2897069726 modified "2023-09-30" @default.
- W2897069726 title "Identifying standardized definitions of treatment response in trichotillomania: A meta-analysis" @default.
- W2897069726 cites W1810378277 @default.
- W2897069726 cites W1845776401 @default.
- W2897069726 cites W1965926889 @default.
- W2897069726 cites W197736987 @default.
- W2897069726 cites W1979826615 @default.
- W2897069726 cites W1991137562 @default.
- W2897069726 cites W2000777543 @default.
- W2897069726 cites W2010261340 @default.
- W2897069726 cites W2022087331 @default.
- W2897069726 cites W2025562320 @default.
- W2897069726 cites W2030985912 @default.
- W2897069726 cites W2037839288 @default.
- W2897069726 cites W2038083244 @default.
- W2897069726 cites W2040527173 @default.
- W2897069726 cites W2051244946 @default.
- W2897069726 cites W2066062428 @default.
- W2897069726 cites W2075079553 @default.
- W2897069726 cites W2091577656 @default.
- W2897069726 cites W2105394173 @default.
- W2897069726 cites W2110882522 @default.
- W2897069726 cites W2117352205 @default.
- W2897069726 cites W2142814663 @default.
- W2897069726 cites W2144691845 @default.
- W2897069726 cites W2156816749 @default.
- W2897069726 cites W2160932918 @default.
- W2897069726 cites W2169160087 @default.
- W2897069726 cites W2325821938 @default.
- W2897069726 cites W2556953528 @default.
- W2897069726 cites W2563497642 @default.
- W2897069726 cites W2617595617 @default.
- W2897069726 cites W2626036701 @default.
- W2897069726 cites W2993744382 @default.
- W2897069726 cites W4239452805 @default.
- W2897069726 cites W72082662 @default.
- W2897069726 doi "https://doi.org/10.1016/j.pnpbp.2018.10.009" @default.
- W2897069726 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30336171" @default.
- W2897069726 hasPublicationYear "2019" @default.
- W2897069726 type Work @default.
- W2897069726 sameAs 2897069726 @default.
- W2897069726 citedByCount "8" @default.
- W2897069726 countsByYear W28970697262020 @default.
- W2897069726 countsByYear W28970697262022 @default.
- W2897069726 countsByYear W28970697262023 @default.
- W2897069726 crossrefType "journal-article" @default.
- W2897069726 hasAuthorship W2897069726A5004690387 @default.
- W2897069726 hasAuthorship W2897069726A5008981904 @default.
- W2897069726 hasAuthorship W2897069726A5011291875 @default.
- W2897069726 hasAuthorship W2897069726A5050882868 @default.
- W2897069726 hasAuthorship W2897069726A5060512263 @default.
- W2897069726 hasConcept C126322002 @default.
- W2897069726 hasConcept C136764020 @default.
- W2897069726 hasConcept C15744967 @default.
- W2897069726 hasConcept C2777382242 @default.
- W2897069726 hasConcept C41008148 @default.
- W2897069726 hasConcept C43346845 @default.
- W2897069726 hasConcept C58471807 @default.
- W2897069726 hasConcept C71924100 @default.
- W2897069726 hasConcept C95190672 @default.
- W2897069726 hasConceptScore W2897069726C126322002 @default.
- W2897069726 hasConceptScore W2897069726C136764020 @default.
- W2897069726 hasConceptScore W2897069726C15744967 @default.
- W2897069726 hasConceptScore W2897069726C2777382242 @default.
- W2897069726 hasConceptScore W2897069726C41008148 @default.
- W2897069726 hasConceptScore W2897069726C43346845 @default.
- W2897069726 hasConceptScore W2897069726C58471807 @default.
- W2897069726 hasConceptScore W2897069726C71924100 @default.
- W2897069726 hasConceptScore W2897069726C95190672 @default.
- W2897069726 hasLocation W28970697261 @default.
- W2897069726 hasLocation W28970697262 @default.
- W2897069726 hasOpenAccess W2897069726 @default.
- W2897069726 hasPrimaryLocation W28970697261 @default.
- W2897069726 hasRelatedWork W2052430535 @default.
- W2897069726 hasRelatedWork W2748952813 @default.
- W2897069726 hasRelatedWork W2899084033 @default.
- W2897069726 hasRelatedWork W3090452522 @default.
- W2897069726 hasRelatedWork W3096305931 @default.
- W2897069726 hasRelatedWork W3120777893 @default.
- W2897069726 hasRelatedWork W4239975450 @default.
- W2897069726 hasRelatedWork W4249952659 @default.
- W2897069726 hasRelatedWork W4306177813 @default.
- W2897069726 hasRelatedWork W2903040050 @default.
- W2897069726 hasVolume "89" @default.
- W2897069726 isParatext "false" @default.
- W2897069726 isRetracted "false" @default.
- W2897069726 magId "2897069726" @default.
- W2897069726 workType "article" @default.