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- W2897069858 abstract "Abstract Animals readily execute learned motor behaviors in a consistent manner over long periods of time, yet similarly stable neural correlates remained elusive up to now. How does the cortex achieve this stable control? Using the sensorimotor system as a model of cortical processing, we investigated the hypothesis that the dynamics of neural latent activity, which capture the dominant co-variation patterns within the neural population, are preserved across time. We recorded from populations of neurons in premotor, primary motor, and somatosensory cortices for up to two years as monkeys performed a reaching task. Intriguingly, despite steady turnover in the recorded neurons, the low-dimensional latent dynamics remained stable. Such stability allowed reliable decoding of behavioral features for the entire timespan, while fixed decoders based on the recorded neural activity degraded substantially. We posit that latent cortical dynamics within the manifold are the fundamental and stable building blocks underlying consistent behavioral execution." @default.
- W2897069858 created "2018-10-26" @default.
- W2897069858 creator A5032665789 @default.
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- W2897069858 date "2018-10-18" @default.
- W2897069858 modified "2023-10-16" @default.
- W2897069858 title "A stable, long-term cortical signature underlying consistent behavior" @default.
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- W2897069858 doi "https://doi.org/10.1101/447441" @default.
- W2897069858 hasPublicationYear "2018" @default.
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