Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897091331> ?p ?o ?g. }
- W2897091331 endingPage "3075" @default.
- W2897091331 startingPage "3075" @default.
- W2897091331 abstract "Ultra-high performance liquid chromatography coupled with photo-diode array detector and electrospray ionization-mass spectrometry was employed to analyze the major fatty acids in Spirulina platensis 95% ethanol extract (SPL95). The effects of SPL95 on hepatoprotection were evaluated, including liver tissue histopathology, liver, and serum biochemical analysis. The active principle of SPL95 revealed a hypolipidemic effect, as indicated by down-regulating the mRNA and protein levels of sterol regulatory element-binding transcription factor-1c, 3-hydroxy-3-methyl glutaryl coenzyme A reductase, acetyl CoA carboxylase pathway, and upregulating adenosine 5′-monophosphate-activated protein kinase-α in liver. SPL95 enriched the beneficial bacteria, including Prevotella, Alloprevotella, Porphyromonadaceae, Barnesiella, and Paraprevotella. Treatment with SPL95 led to a decrease in microbes, such as Turicibacter, Romboutsia, Phascolarctobacterium, Olsenella, and Clostridium XVIII, which were positively correlated with serum triglyceride, total cholesterol, and low-density-lipoprotein cholesterol levels, but negatively correlated with the serum high-density-lipoprotein cholesterol levels. These results provide evidence that the fatty acid from SPL95 may be used as a novel adjuvant therapy and functional food to regulate gut microbiota in obese and diabetic individuals." @default.
- W2897091331 created "2018-10-26" @default.
- W2897091331 creator A5016163193 @default.
- W2897091331 creator A5033006259 @default.
- W2897091331 creator A5047622041 @default.
- W2897091331 creator A5049664413 @default.
- W2897091331 creator A5067018911 @default.
- W2897091331 creator A5086525158 @default.
- W2897091331 date "2018-10-09" @default.
- W2897091331 modified "2023-10-14" @default.
- W2897091331 title "Regulatory Efficacy of the Polyunsaturated Fatty Acids from Microalgae Spirulina platensis on Lipid Metabolism and Gut Microbiota in High-Fat Diet Rats" @default.
- W2897091331 cites W1261776069 @default.
- W2897091331 cites W1494321569 @default.
- W2897091331 cites W1500847299 @default.
- W2897091331 cites W1791446235 @default.
- W2897091331 cites W1844490078 @default.
- W2897091331 cites W1944741194 @default.
- W2897091331 cites W1978058114 @default.
- W2897091331 cites W1979000812 @default.
- W2897091331 cites W2002542540 @default.
- W2897091331 cites W2024994058 @default.
- W2897091331 cites W2048615871 @default.
- W2897091331 cites W2082216141 @default.
- W2897091331 cites W2093727198 @default.
- W2897091331 cites W2126842666 @default.
- W2897091331 cites W2144275312 @default.
- W2897091331 cites W2145783127 @default.
- W2897091331 cites W2146544786 @default.
- W2897091331 cites W2158594746 @default.
- W2897091331 cites W2170964075 @default.
- W2897091331 cites W2176878760 @default.
- W2897091331 cites W2177293833 @default.
- W2897091331 cites W2188894310 @default.
- W2897091331 cites W2354595720 @default.
- W2897091331 cites W2413770535 @default.
- W2897091331 cites W2466878065 @default.
- W2897091331 cites W2519159149 @default.
- W2897091331 cites W2549568832 @default.
- W2897091331 cites W2585660757 @default.
- W2897091331 cites W2650260085 @default.
- W2897091331 cites W2670032958 @default.
- W2897091331 cites W2738132656 @default.
- W2897091331 cites W2773946960 @default.
- W2897091331 cites W2774396140 @default.
- W2897091331 cites W2790886845 @default.
- W2897091331 cites W2792696219 @default.
- W2897091331 cites W2902446450 @default.
- W2897091331 cites W4252021281 @default.
- W2897091331 doi "https://doi.org/10.3390/ijms19103075" @default.
- W2897091331 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6213792" @default.
- W2897091331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30304774" @default.
- W2897091331 hasPublicationYear "2018" @default.
- W2897091331 type Work @default.
- W2897091331 sameAs 2897091331 @default.
- W2897091331 citedByCount "56" @default.
- W2897091331 countsByYear W28970913312018 @default.
- W2897091331 countsByYear W28970913312019 @default.
- W2897091331 countsByYear W28970913312020 @default.
- W2897091331 countsByYear W28970913312021 @default.
- W2897091331 countsByYear W28970913312022 @default.
- W2897091331 countsByYear W28970913312023 @default.
- W2897091331 crossrefType "journal-article" @default.
- W2897091331 hasAuthorship W2897091331A5016163193 @default.
- W2897091331 hasAuthorship W2897091331A5033006259 @default.
- W2897091331 hasAuthorship W2897091331A5047622041 @default.
- W2897091331 hasAuthorship W2897091331A5049664413 @default.
- W2897091331 hasAuthorship W2897091331A5067018911 @default.
- W2897091331 hasAuthorship W2897091331A5086525158 @default.
- W2897091331 hasBestOaLocation W28970913311 @default.
- W2897091331 hasConcept C185592680 @default.
- W2897091331 hasConcept C18903297 @default.
- W2897091331 hasConcept C19038510 @default.
- W2897091331 hasConcept C206139338 @default.
- W2897091331 hasConcept C2778163477 @default.
- W2897091331 hasConcept C2778718757 @default.
- W2897091331 hasConcept C2778913445 @default.
- W2897091331 hasConcept C2779784034 @default.
- W2897091331 hasConcept C4733338 @default.
- W2897091331 hasConcept C48289651 @default.
- W2897091331 hasConcept C539455810 @default.
- W2897091331 hasConcept C543025807 @default.
- W2897091331 hasConcept C55493867 @default.
- W2897091331 hasConcept C85051948 @default.
- W2897091331 hasConcept C86803240 @default.
- W2897091331 hasConceptScore W2897091331C185592680 @default.
- W2897091331 hasConceptScore W2897091331C18903297 @default.
- W2897091331 hasConceptScore W2897091331C19038510 @default.
- W2897091331 hasConceptScore W2897091331C206139338 @default.
- W2897091331 hasConceptScore W2897091331C2778163477 @default.
- W2897091331 hasConceptScore W2897091331C2778718757 @default.
- W2897091331 hasConceptScore W2897091331C2778913445 @default.
- W2897091331 hasConceptScore W2897091331C2779784034 @default.
- W2897091331 hasConceptScore W2897091331C4733338 @default.
- W2897091331 hasConceptScore W2897091331C48289651 @default.
- W2897091331 hasConceptScore W2897091331C539455810 @default.
- W2897091331 hasConceptScore W2897091331C543025807 @default.
- W2897091331 hasConceptScore W2897091331C55493867 @default.
- W2897091331 hasConceptScore W2897091331C85051948 @default.