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• W2897094734 abstract "NOAH (NMR by Ordered Acquisition using 1H-detection) type of pure shift NMR pulse scheme has been designed for the efficient utilization of magnetization that presents in a spin-system under consideration. The proposed strategy, PROSMASH-HSQC2 (PROtein-HSQC and SMAll molecule-HSQC Signals with Homodecoupling) uses the real-time BIRD pure shift NMR strategy and two HSQC spectra (13C-HSQC for small molecules and 15N-HSQC for 15N-isotopic labelled proteins) can be recorded in a single NMR experiment. Thus, this method permits precise determination of drug-protein interactions at atomic levels by monitoring the chemical shift perturbations, and will have potential applications in drug discovery programs." @default.
• W2897094734 created "2018-10-26" @default.
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• W2897094734 date "2018-12-01" @default.
• W2897094734 modified "2023-10-17" @default.
• W2897094734 title "NMR supersequences with real-time homonuclear broadband decoupling: Sequential acquisition of protein and small molecule spectra in a single experiment" @default.
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• W2897094734 doi "https://doi.org/10.1016/j.jmr.2018.10.013" @default.
• W2897094734 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30384129" @default.
• W2897094734 hasPublicationYear "2018" @default.
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