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- W2897095881 abstract "Dementia of Alzheimer's type (DAT) is a neurodegenerative disorder that is characterized by progressive cognitive deterioration and decline in activities of daily living (ADLs). Among the cognitive deficits, attention is the first non- memory domain to be affected in DAT. In particular, the neurocognitive research on DAT patients showed an impairment in performance on tasks requiring controlled inhibition i.e. executive control processes. Further, the ability to maintain alert is also affected in the early stages of DAT. These attentional processes influence each other and studies found that the executive control performance is inhibited by the alerting performance. Using attentional network paradigm, the present study examined the effect of phasic alertness on executive control system in patients with mild cognitive impairment (MCI), DAT and healthy controls. The Attentional Network Task (ANT) was used in this study, which comprised of a spatial cued reaction time task, to assess alerting and orienting and a flanker task to assess executive control. In this study an auditory and visual alerting cue was incorporated to compare the cross modal attentional processing on executive control network. The reaction time and performance accuracy of the participants were recorded. The interaction between auditory alerting cue and executive control was significant. The executive control effect was significantly larger in auditory alerting cue conditions than in visual alerting cue conditions. The analysis revealed that functioning of executive control network was improved under auditory alerting cue than visual alerting cue condition." @default.
- W2897095881 created "2018-10-26" @default.
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- W2897095881 date "2018-07-01" @default.
- W2897095881 modified "2023-10-16" @default.
- W2897095881 title "P1‐571: INTERACTION BETWEEN PHASIC ALERTING AND EXECUTIVE CONTROL IN PATIENTS WITH MCI AND PATIENTS WITH EARLY DEMENTIA OF THE ALZHEIMER'S TYPE" @default.
- W2897095881 doi "https://doi.org/10.1016/j.jalz.2018.06.583" @default.
- W2897095881 hasPublicationYear "2018" @default.
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