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- W2897112760 abstract "This study examined cutaneous vasoconstriction to whole-body hypothermia, specifically contributions of neural and endothelial vasomotor responses in glabrous and non-glabrous skin. Eleven participants were semi-recumbent at an ambient temperature of 22 °C for 30 min, after which ambient temperature was decreased to 0 °C until rectal temperature (Tre) had decreased by 0.5 °C. Laser-Doppler fluxmetry was measured at the forehead and thigh for measures of glabrous and non-glabrous skin, respectively; wavelet analysis was performed on the laser-Doppler signal to determine endothelial and neural activities. Hypothermia took on average 97 ± 7 min and caused marked decreases at glabrous (42 ± 5%baseline, p < 0.001) and non-glabrous (69 ± 4%baseline, p < 0.001) skin. In glabrous skin, neural activity increased from 11 ± 1% at thermoneutral to 18 ± 1% (p < 0.001). In non-glabrous skin there was an initial decrease (p = 0.001) in neural activity from 13 ± 2% to 9 ± 1% (-0.2 °C decrease in Tre) and then increased (p = 0.002) to 21 ± 2% baseline at -0.5 °C Tre. Endothelial activity decreased in both glabrous (16 ± 3% to 6 ± 1%, p < 0.001) and non-glabrous (15 ± 1% to 7 ± 1%, p = 0.003) skin. Hypothermia elicits large decreases in skin blood flow in both glabrous and non-glabrous skin that are related to increases in neural activity and a reduction of endothelial activity." @default.
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- W2897112760 date "2019-01-01" @default.
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- W2897112760 title "Glabrous and non-glabrous vascular responses to mild hypothermia" @default.
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- W2897112760 doi "https://doi.org/10.1016/j.mvr.2018.10.006" @default.
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