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- W2897138816 abstract "BACKGROUND:There is a complex relationship between sleep and epilepsy. They are reciprocal to each other.METHOD:A total of 30 generalized tonic clonic seizure patients and 30 controls were subjected to polysomnography. It simultaneously records the three physiological measures that define the stages of muscle tone, recorded throughElectromyogram (EMG), eye movements, recorded through the Electrooculogram (EOG) and brain activity, recorded through the Electroencephalogram (EEG), and compared with equal number of normal individuals. Ghrelin is peptide hormone, secreted from stomach. Its level was measured in the fasting state. Its level increased before food intake anddecreased after food intake.RESULTS:The mean age of the study groups were comparable 31.10±5.6 for GTCS patients and 30.03±6.26 for control groups as well as body mass index for GTCS patients (26.89±0.99) and for control groups (26.30±1.46). In this study, sleep architectural changes, mainly prolonged stage I (18.35±2.85 for GTCS and 14.6±2.6 f0r control group)and stage II of NREM sleep and reduced REM sleep(63.93±13.21 for GTCS and 77.27±13.3 for control group) occurs in GTCS patients than comparative with control group leads to fragmentation of sleep. And also serum ghrelin levels were decreased in these patients.CONCLUSION:Sleep disturbances are more common in the epileptic patients. It will further worsening the seizure propensity. Identifying and treating these associated sleep problems, also an important part in the management of epilepsy." @default.
- W2897138816 created "2018-10-26" @default.
- W2897138816 creator A5090441238 @default.
- W2897138816 date "2015-04-01" @default.
- W2897138816 modified "2023-09-24" @default.
- W2897138816 title "A Study of Polysomnography and Serum Ghrelin Levels in Patients with Generalized Tonicclonic Seizures" @default.
- W2897138816 hasPublicationYear "2015" @default.
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