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- W2897150246 abstract "Varicose vein treatment has been directed toward less invasive yet lasting techniques. This study was designed to compare the effectiveness of cyanoacrylate ablation (CAA) with that of radiofrequency ablation (RFA). The study included 524 and 202 patients who had undergone RFA (ClosureFast; Medtronic, San Jose, Calif) and CAA (VenaBlock Venous Closure System; Invamed, Ankara, Turkey), respectively, within the preceding 4 years. The mean age of the patients was 48.4 ± 11.3 years, and the mean follow-up time was 24.3 ± 3.2 months. Preoperative and postoperative Clinical, Etiology, Anatomy, and Pathophysiology (CEAP) class, symptoms, recurrence, and Doppler findings of the two groups were compared. Postoperative Doppler saphenous vein closure rates were 97.3% in the RFA group and 98.7% in the CAA group. The type of operation had no effect on postoperative symptoms, CEAP class, or Doppler findings. There is no efficiency difference between treatment methods. The predictors of postoperative CEAP class were preoperative CEAP class, bilateral limb disease, and prior deep venous thrombosis, whereas the predictors of symptom recurrence were postoperative perforator incompetence and preoperative CEAP class. The 2-year symptom-free survival rates were 66.3% in the RFA group and 61.9% in the CAA group. The Venous Clinical Severity Score decreased from 5.9 ± 1.1 to 0.8 ± 0.8 in the RFA group and from 5.7 ± 0.9 to 0.7 ± 0.6 in the CAA group. The Aberdeen Varicose Vein Questionnaire score decreased from 19.6 ± 5.4 to 4.8 ± 1.4 in the RFA group and from 18.7 ± 5.7 to 4.9 ± 1.3 in the CAA group. The major disadvantages of current thermal ablation techniques, such as postoperative pain and discomfort as well as skin bruises, paresthesia, and burns caused by thermal damage, and the need for tumescent anesthesia caused an increasing need for the development of nonthermal, nontumescent options for shorter and more successful treatment of venous insufficiency. The CAA seems to be the closest technique to the ideal and suitable for all patients because it is nonthermal and nontumescent. The results are satisfactory and are comparable to those of RFA. When two techniques are evaluated, CAA may be preferable as a simple application in a shorter time with less early postoperative discomfort. However, long-term results and cost analyses of larger series still need to be documented." @default.
- W2897150246 created "2018-10-26" @default.
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- W2897150246 date "2018-11-01" @default.
- W2897150246 modified "2023-10-18" @default.
- W2897150246 title "LUE 1. A Comparative Analysis of the Results of Cyanoacrylate Ablation and Radiofrequency Ablation in the Treatment of Venous Insufficiency" @default.
- W2897150246 doi "https://doi.org/10.1016/j.jvs.2018.08.130" @default.
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