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- W2897156660 abstract "To assess the influence of microRNA-183 (miR-183) on the migration and invasion of A375 human melanoma cells, an A375 cell line with stable miR-183 overexpression or knockdown was constructed using lentiviral transfection. The change of miR-183 expression in these cells and in non-transfected controls was verified using reverse transcription-quantitative polymerase chain reaction. The impact of miR-183 on experimental A375 cell migration and invasion was assessed using a scratch and Transwell assay. The expression of Ezrin and matrix metalloprotease-9 (MMP-9), which are two mediator proteins that serve roles in tumor cell migration and invasion, were analyzed in each cell group via western blotting. The results of the present study indicated that miR-183 overexpression significantly inhibits A375 cell migration and invasion, which may be facilitated by miR-183 knockdown. Furthermore, Ezrin and MMP-9 protein levels were negatively associated with miR-183 expression, indicating that miR-183 may function as a tumor suppressor by inhibiting the expression of these two proteins. Additionally, miR-183 downregulation may be associated with the progression of melanoma." @default.
- W2897156660 created "2018-10-26" @default.
- W2897156660 creator A5038357504 @default.
- W2897156660 creator A5059507717 @default.
- W2897156660 date "2018-10-22" @default.
- W2897156660 modified "2023-09-29" @default.
- W2897156660 title "MicroRNA‑183 inhibits A375 human melanoma cell migration and invasion by targeting Ezrin and MMP‑9" @default.
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- W2897156660 cites W1952485984 @default.
- W2897156660 cites W1964357419 @default.
- W2897156660 cites W1970234497 @default.
- W2897156660 cites W1980383541 @default.
- W2897156660 cites W1991313260 @default.
- W2897156660 cites W1997006882 @default.
- W2897156660 cites W2005252392 @default.
- W2897156660 cites W2012144636 @default.
- W2897156660 cites W2012422571 @default.
- W2897156660 cites W2013329576 @default.
- W2897156660 cites W2016534280 @default.
- W2897156660 cites W2049444331 @default.
- W2897156660 cites W2052358899 @default.
- W2897156660 cites W2060862824 @default.
- W2897156660 cites W2061308066 @default.
- W2897156660 cites W2062332185 @default.
- W2897156660 cites W2073849606 @default.
- W2897156660 cites W2074578444 @default.
- W2897156660 cites W2075629467 @default.
- W2897156660 cites W2077344825 @default.
- W2897156660 cites W2084526459 @default.
- W2897156660 cites W2084922406 @default.
- W2897156660 cites W2086260986 @default.
- W2897156660 cites W2087108553 @default.
- W2897156660 cites W2089370460 @default.
- W2897156660 cites W2097341442 @default.
- W2897156660 cites W2107277218 @default.
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- W2897156660 cites W2167835377 @default.
- W2897156660 cites W2170618275 @default.
- W2897156660 cites W2187482341 @default.
- W2897156660 cites W2197153978 @default.
- W2897156660 cites W2204746834 @default.
- W2897156660 cites W2266642462 @default.
- W2897156660 cites W2266659175 @default.
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- W2897156660 cites W2297975469 @default.
- W2897156660 cites W2306942974 @default.
- W2897156660 cites W2317989419 @default.
- W2897156660 cites W2334189061 @default.
- W2897156660 cites W2336531131 @default.
- W2897156660 cites W2338560560 @default.
- W2897156660 cites W2395875162 @default.
- W2897156660 cites W2408053823 @default.
- W2897156660 cites W2408234422 @default.
- W2897156660 cites W2415018300 @default.
- W2897156660 cites W2415411295 @default.
- W2897156660 cites W2415752733 @default.
- W2897156660 cites W2435203082 @default.
- W2897156660 cites W2476274315 @default.
- W2897156660 cites W2491895975 @default.
- W2897156660 cites W2518808027 @default.
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- W2897156660 cites W2579485436 @default.
- W2897156660 cites W2594321122 @default.
- W2897156660 cites W2595446467 @default.
- W2897156660 cites W2601868035 @default.
- W2897156660 cites W2601887934 @default.
- W2897156660 cites W2604068828 @default.
- W2897156660 cites W2604084641 @default.
- W2897156660 cites W2610489211 @default.
- W2897156660 cites W2615987098 @default.
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- W2897156660 cites W2790838105 @default.
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- W2897156660 doi "https://doi.org/10.3892/ol.2018.9603" @default.
- W2897156660 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6313199" @default.
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- W2897156660 hasPublicationYear "2018" @default.
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