FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897166603> ?p ?o ?g. }

• W2897166603 endingPage "25699" @default.
• W2897166603 startingPage "25692" @default.
• W2897166603 abstract "As the concentration of amphiphilic invertible polymers (AIPs) in both polar and nonpolar solvents increases, the AIP macromolecules self-assemble into polymeric micelles. The resulting invertible micellar assemblies (IMAs) have a controlled size and morphology determined by macromolecular composition and hydrophilic lipophilic balance (HLB) of the AIPs. It has been demonstrated that AIPs can rapidly switch the conformation in response to changes in the environmental polarity, thus facilitating, micellar inversion. In combination with IMAs’ ability to solubilize otherwise insoluble substances, inversion can be promising for rapid and controlled cargo delivery and release in applications that require simultaneous utility in polar and nonpolar media. While IMAs have been demonstrated to interact with peptides, fundamental pictures of micellar inversion remain elusive and became the focus of this work, including the behavior of the incorporated peptide in IMAs at the molecular level at different polarities of the environment and how polymer composition impacts such behavior. To trigger conformational changes of the micelle-forming AIPs, acetone (no self-assembly occurs in acetone) was added into the peptide-loaded IMAs aqueous solutions. Electron Paramagnetic Resonance (EPR) in combination with peptide spin labeling was used to probe the local environment of an antigenic peptide at various acetone concentrations. The obtained results are consistent with the previously revealed micellar structure. Increasing acetone percentage clearly impacts the extent of IMA inversion as reported by the labeled peptide and quantified by semiquantitative spectral analysis. The conformational changes are different for the two AIPs differing in the macromolecular composition. Conformational changes clearly relate to the HLB of the AIPs macromolecules and can certainly be meaningful in controlling the IMAs-mediated peptide release." @default.
• W2897166603 created "2018-10-26" @default.
• W2897166603 creator A5012931603 @default.
• W2897166603 creator A5047764948 @default.
• W2897166603 creator A5084400126 @default.
• W2897166603 creator A5087837884 @default.
• W2897166603 date "2018-10-22" @default.
• W2897166603 modified "2023-10-15" @default.
• W2897166603 title "Inversion of Polymeric Micelles Probed by Spin Labeled Peptide Incorporation and Electron Paramagnetic Resonance" @default.
• W2897166603 cites W1858237937 @default.
• W2897166603 cites W1975933723 @default.
• W2897166603 cites W1982494241 @default.
• W2897166603 cites W1983408077 @default.
• W2897166603 cites W1989846852 @default.
• W2897166603 cites W1991898265 @default.
• W2897166603 cites W1998367193 @default.
• W2897166603 cites W2004645398 @default.
• W2897166603 cites W2006013008 @default.
• W2897166603 cites W2008812223 @default.
• W2897166603 cites W2009488132 @default.
• W2897166603 cites W2036389108 @default.
• W2897166603 cites W2044712738 @default.
• W2897166603 cites W2052398271 @default.
• W2897166603 cites W2057312784 @default.
• W2897166603 cites W2066589127 @default.
• W2897166603 cites W2077255853 @default.
• W2897166603 cites W2091016067 @default.
• W2897166603 cites W2095224834 @default.
• W2897166603 cites W2108902702 @default.
• W2897166603 cites W2128677332 @default.
• W2897166603 cites W2129052308 @default.
• W2897166603 cites W2153824605 @default.
• W2897166603 cites W2180485882 @default.
• W2897166603 cites W2322715116 @default.
• W2897166603 cites W2326142285 @default.
• W2897166603 cites W2329253962 @default.
• W2897166603 cites W2330085727 @default.
• W2897166603 cites W2461307944 @default.
• W2897166603 cites W2606120703 @default.
• W2897166603 cites W2752919771 @default.
• W2897166603 cites W2758816225 @default.
• W2897166603 cites W2769239098 @default.
• W2897166603 cites W2051292382 @default.
• W2897166603 doi "https://doi.org/10.1021/acs.jpcc.8b09206" @default.
• W2897166603 hasPublicationYear "2018" @default.
• W2897166603 type Work @default.
• W2897166603 sameAs 2897166603 @default.
• W2897166603 citedByCount "11" @default.
• W2897166603 countsByYear W28971666032019 @default.
• W2897166603 countsByYear W28971666032020 @default.
• W2897166603 countsByYear W28971666032021 @default.
• W2897166603 countsByYear W28971666032022 @default.
• W2897166603 countsByYear W28971666032023 @default.
• W2897166603 crossrefType "journal-article" @default.
• W2897166603 hasAuthorship W2897166603A5012931603 @default.
• W2897166603 hasAuthorship W2897166603A5047764948 @default.
• W2897166603 hasAuthorship W2897166603A5084400126 @default.
• W2897166603 hasAuthorship W2897166603A5087837884 @default.
• W2897166603 hasConcept C11268172 @default.
• W2897166603 hasConcept C121332964 @default.
• W2897166603 hasConcept C15920480 @default.
• W2897166603 hasConcept C177462420 @default.
• W2897166603 hasConcept C178790620 @default.
• W2897166603 hasConcept C184651966 @default.
• W2897166603 hasConcept C185592680 @default.
• W2897166603 hasConcept C187961010 @default.
• W2897166603 hasConcept C204389451 @default.
• W2897166603 hasConcept C2779281246 @default.
• W2897166603 hasConcept C41625074 @default.
• W2897166603 hasConcept C46141821 @default.
• W2897166603 hasConcept C521977710 @default.
• W2897166603 hasConcept C55493867 @default.
• W2897166603 hasConcept C67407626 @default.
• W2897166603 hasConcept C8010536 @default.
• W2897166603 hasConceptScore W2897166603C11268172 @default.
• W2897166603 hasConceptScore W2897166603C121332964 @default.
• W2897166603 hasConceptScore W2897166603C15920480 @default.
• W2897166603 hasConceptScore W2897166603C177462420 @default.
• W2897166603 hasConceptScore W2897166603C178790620 @default.
• W2897166603 hasConceptScore W2897166603C184651966 @default.
• W2897166603 hasConceptScore W2897166603C185592680 @default.
• W2897166603 hasConceptScore W2897166603C187961010 @default.
• W2897166603 hasConceptScore W2897166603C204389451 @default.
• W2897166603 hasConceptScore W2897166603C2779281246 @default.
• W2897166603 hasConceptScore W2897166603C41625074 @default.
• W2897166603 hasConceptScore W2897166603C46141821 @default.
• W2897166603 hasConceptScore W2897166603C521977710 @default.
• W2897166603 hasConceptScore W2897166603C55493867 @default.
• W2897166603 hasConceptScore W2897166603C67407626 @default.
• W2897166603 hasConceptScore W2897166603C8010536 @default.
• W2897166603 hasIssue "44" @default.
• W2897166603 hasLocation W28971666031 @default.
• W2897166603 hasOpenAccess W2897166603 @default.
• W2897166603 hasPrimaryLocation W28971666031 @default.
• W2897166603 hasRelatedWork W1971704817 @default.
• W2897166603 hasRelatedWork W2032167311 @default.
• W2897166603 hasRelatedWork W2065807099 @default.
• W2897166603 hasRelatedWork W2375460683 @default.

• next