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- W2897225624 endingPage "373" @default.
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- W2897225624 abstract "Ocular in situ gels are a promising alternative to overcome drawbacks of conventional eye drops because they associate the advantages of solutions such as accuracy and reproducibility of dosing, or ease of administration with prolonged contact time of ointments. Chitosan is a natural polymer suitable for use in ophthalmic formulations due to its biocompatibility, biodegradability, mucoadhesive character, antibacterial and antifungal properties, permeation enhancement and corneal wound healing effects. The combination of chitosan, pH-sensitive polymer, with other stimuli-responsive polymers leads to increased mechanical strength of formulations and an improved therapeutic effect due to prolonged ocular contact time. This review describes in situ gelling systems resulting from the association of chitosan with various stimuli-responsive polymers with emphasis on the mechanism of gel formation and application in ophthalmology. It also comprises the main techniques for evaluation of chitosan in situ gels, along with requirements of safety and ocular tolerability." @default.
- W2897225624 created "2018-10-26" @default.
- W2897225624 creator A5015553981 @default.
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- W2897225624 creator A5084318183 @default.
- W2897225624 date "2018-10-09" @default.
- W2897225624 modified "2023-10-16" @default.
- W2897225624 title "Chitosan-Based In Situ Gels for Ocular Delivery of Therapeutics: A State-of-the-Art Review" @default.
- W2897225624 cites W1475796694 @default.
- W2897225624 cites W1877301297 @default.
- W2897225624 cites W1949073676 @default.
- W2897225624 cites W1964766613 @default.
- W2897225624 cites W1964916662 @default.
- W2897225624 cites W1965473741 @default.
- W2897225624 cites W1967267374 @default.
- W2897225624 cites W1970440361 @default.
- W2897225624 cites W1971680873 @default.
- W2897225624 cites W1976372264 @default.
- W2897225624 cites W1977179933 @default.
- W2897225624 cites W1979565474 @default.
- W2897225624 cites W1981568312 @default.
- W2897225624 cites W1987087659 @default.
- W2897225624 cites W1988413525 @default.
- W2897225624 cites W1990894011 @default.
- W2897225624 cites W1999657637 @default.
- W2897225624 cites W2004641254 @default.
- W2897225624 cites W2008930614 @default.
- W2897225624 cites W2011977414 @default.
- W2897225624 cites W2019124060 @default.
- W2897225624 cites W2020384545 @default.
- W2897225624 cites W2020473652 @default.
- W2897225624 cites W2021152168 @default.
- W2897225624 cites W2030606945 @default.
- W2897225624 cites W2032931324 @default.
- W2897225624 cites W2033563967 @default.
- W2897225624 cites W2049818440 @default.
- W2897225624 cites W2050323177 @default.
- W2897225624 cites W2053724045 @default.
- W2897225624 cites W2063110356 @default.
- W2897225624 cites W2064308610 @default.
- W2897225624 cites W2072018844 @default.
- W2897225624 cites W2074913648 @default.
- W2897225624 cites W2074980407 @default.
- W2897225624 cites W2075216419 @default.
- W2897225624 cites W2077799930 @default.
- W2897225624 cites W2084031482 @default.
- W2897225624 cites W2085252235 @default.
- W2897225624 cites W2085648623 @default.
- W2897225624 cites W2090044999 @default.
- W2897225624 cites W2091403293 @default.
- W2897225624 cites W2126424209 @default.
- W2897225624 cites W2130894493 @default.
- W2897225624 cites W2133578093 @default.
- W2897225624 cites W2139516405 @default.
- W2897225624 cites W2144780027 @default.
- W2897225624 cites W2147620881 @default.
- W2897225624 cites W2153324098 @default.
- W2897225624 cites W2154659743 @default.
- W2897225624 cites W2158643446 @default.
- W2897225624 cites W2158990016 @default.
- W2897225624 cites W2179527096 @default.
- W2897225624 cites W2193900939 @default.
- W2897225624 cites W2196391893 @default.
- W2897225624 cites W2196611084 @default.
- W2897225624 cites W2266732512 @default.
- W2897225624 cites W2266947885 @default.
- W2897225624 cites W2310821971 @default.
- W2897225624 cites W2322703639 @default.
- W2897225624 cites W2324350546 @default.
- W2897225624 cites W2328984514 @default.
- W2897225624 cites W2333426652 @default.
- W2897225624 cites W2336504073 @default.
- W2897225624 cites W2346306482 @default.
- W2897225624 cites W2469037914 @default.
- W2897225624 cites W2508192836 @default.
- W2897225624 cites W2520203262 @default.
- W2897225624 cites W2535780103 @default.
- W2897225624 cites W2539812081 @default.
- W2897225624 cites W2565842908 @default.
- W2897225624 cites W2571692136 @default.
- W2897225624 cites W2572308911 @default.
- W2897225624 cites W2581108109 @default.
- W2897225624 cites W2592374624 @default.
- W2897225624 cites W2604726080 @default.
- W2897225624 cites W2606251873 @default.
- W2897225624 cites W2610730976 @default.
- W2897225624 cites W2626671348 @default.
- W2897225624 cites W2734723409 @default.
- W2897225624 cites W2735027836 @default.
- W2897225624 cites W2737085547 @default.
- W2897225624 cites W2751053137 @default.
- W2897225624 cites W2752014220 @default.
- W2897225624 cites W2758048874 @default.
- W2897225624 cites W2767809152 @default.