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• W2897225921 abstract "The objective of this study was to evaluate the relationship between the neutrophil/lymphocyte ratio and the presence of signs of arthrosis in both hips in patients followed at this medical center. This was a cross-sectional, retrospective study through the analysis of medical records and database review of patients over 18 years of age with hip arthrosis, followed at the outpatient clinic of this hospital. Regarding the analysis of the Mann–Whitney test to correlate the neutrophil/lymphocyte ratio and laterality, a bi-lateral test result of p = 0.036 was obtained, thus demonstrating a significant difference between the observed groups. When we analyzed the absolute values of neutrophils and lymphocytes, the authors obtained results of p = 0.14 and p = 0.24. Therefore, it was not possible to observe statistically significant differences between the absolute values in the two groups. Considering the interactions between the inflammatory mechanisms in osteoarthritis and the fact that the interaction between neutrophils and lymphocytes has differences in relation to the laterality of the coxarthrosis, it is hypothesized that the inflammatory etiology of unilateral and bilateral osteoarthritis could have different dynamics. However, more in-depth studies with flow cytometry are needed to assess the possible impact of these differences in the inflammatory mechanisms observed in this study. Avaliar a relação entre a razão neutrófilo/linfócito e a presença de sinais de artrose em ambos os quadris em pacientes acompanhados neste serviço. Estudo transversal, retrospectivo, que usou análise de prontuários e revisão de banco de dados de pacientes maiores de 18 anos com diagnóstico de artrose de quadril acompanhados no ambulatório deste hospital. Com relação à análise do teste de Mann-Whitney para correlacionar a razão neutrófilo/linfócito e a lateralidade, observou-se um resultado de teste bilateral de 0,036, evidenciou desse modo a diferença entre os grupos. Quando os valores absolutos de neutrófilos e linfócitos foram analisados, observaram-se p = 0,14 e p = 0,24, não foi possível observar diferenças estatisticamente significativas entre os valores absolutos nos dois grupos. Considerando-se as interações entre os mecanismos inflamatórios na osteoartrose e o fato de que a interação entre os neutrófilos e os linfócitos tem diferenças com relação à lateralidade da coxartrose, é possível levantar a hipótese de que a etiologia inflamatória da osteoartrose unilateral e da bilateral tem dinâmicas diferentes. Entretanto, são necessários estudos mais aprofundados, com citometria de fluxo, para avaliar o impacto com relação às diferenças nos mecanismos inflamatórios observados nesse estudo." @default.
• W2897225921 created "2018-10-26" @default.
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• W2897225921 date "2018-11-01" @default.
• W2897225921 modified "2023-09-23" @default.
• W2897225921 title "Is there a relationship between the neutrophil/lymphocyte ratio and bilaterality in patients with coxarthrosis?" @default.
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• W2897225921 doi "https://doi.org/10.1016/j.rboe.2017.09.011" @default.
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