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• W2897234823 abstract "There is some evidence to suggest that poor social connections are associated with poor cognitive function in older people who are not experiencing mental health problems, and the trajectory of this association is moderated by cognitive reserve. However, it is not clear whether this relationship is the same for older people with mental health problems. Mental health problems are also associated with poor cognitive function and difficulties in social relationships. Therefore, we aimed to explore social relationships and cognitive function in older people with mental health problems. Baseline and two year follow-up data were analysed from the Cognitive Function and Ageing Study–Wales (CFAS-Wales). ANCOVAs were conducted to compare differences in social isolation, loneliness, social contact, cognitive function, and cognitive reserve at baseline amongst older people with and without mental health problems (N = 2,135). Linear regression modelling was used to assess the relationship between social isolation and cognition in a subgroup of older people with mental health problems (N = 186) and moderation analysis was used to test the moderating effect of cognitive reserve. Older people with mental health problems perceived themselves as more isolated and lonely than those without mental health problems, despite having an equivalent level of social contact with friends and family. In people with mental health problems, social isolation was associated with poor cognitive function at baseline, but not with cognitive change at two year follow-up. Cognitive reserve did not moderate this association. 57% of the people who were experiencing clinically relevant symptoms of depression or anxiety at baseline were no longer experiencing these symptoms at two year follow-up. Social isolation may be associated with poor cognitive function in people with mental health problems at baseline. The observation that cognitive function does not decrease over two years may be attributed to the improvement in symptoms associated with mental health over the two year follow-up period. This has important implications for interventions aiming to enhance mental health and social contact in later life." @default.
• W2897234823 created "2018-10-26" @default.
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• W2897234823 date "2018-07-01" @default.
• W2897234823 modified "2023-10-16" @default.
• W2897234823 title "P4‐185: SOCIAL ISOLATION, COGNITIVE RESERVE, AND COGNITION IN OLDER PEOPLE WITH MENTAL HEALTH PROBLEMS" @default.
• W2897234823 doi "https://doi.org/10.1016/j.jalz.2018.06.2590" @default.
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