Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897299802> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2897299802 endingPage "299" @default.
- W2897299802 startingPage "299" @default.
- W2897299802 abstract "Background Human freeze-dried bone (h-FDB) are widely used to increase bone volume to accommodate osseointegrated implants. Aim/Hypothesis To assess the extent of osseointegration and new bone formation of SLA roughed surface implants placed in FDB blocks or FDB particulate ones. Material and Methods 12 pairs of h-FDB blocks were stabilized bilaterally to the calvaria of twelve rabbits. At 4-month post grafting, SLA implants (4.2 × 6.0-mm) were placed. One block in each pair was chosen for a circumferential tunnel around the implant, which was packed with human cortico-cancellous particles. At 6 and 7 weeks post operatively, fluorochrome bone labeling was carried. Block biopsies were obtained for non-decalcification processing and histological analysis at 6 months, post implant placement. RNA extraction was performed from whole bone (calvaria) and block. RT-PCR was conducted for Tartrate-Resistant Acid Phosphatase (TRAP) and Alkaline Phosphatase (ALP). Morphometric measurements, using Bio-quant Nova software, evaluated bone-to-implant contact (BIC) and bone area fraction (BAF) parameters. A paired t test was applied for statistical analysis. Results Morphometric measurements showed that the mean BIC and BAF within the h-FDB block was 34.4% and 23.9%, respectively. The mean BIC and BAF within the particulate h-FDB was 33.6% and 26.4%, respectively. Differences were non-significant. Statistical analysis for the RNA expression showed significantly higher values only for the ALP counts (16.7−1 + P < 0.05), however, not for the TRAP (2.25−1 + NS) for the particulated group compared to the block group. The fluorescent labeling demonstrated bone modeling and remodeling mainly in proximity to the calvaria in both types of grafts. Conclusions and Clinical Implications Limited osseointegration and newly-formed bone were evident, primarily in the vicinity of the host rabbit calvaria. Despite the elevated osteoblastic activity in the particulate group, there were no significant differences between the groups. The proximity to the recipient osseous host bed is of utmost importance to achieve vascularization and vitalization of the grafted biomaterial. It appears, that the main obstacle is to establish total vitalization of the grafted h-FDB in both forms." @default.
- W2897299802 created "2018-10-26" @default.
- W2897299802 creator A5030154671 @default.
- W2897299802 creator A5039628913 @default.
- W2897299802 creator A5043918394 @default.
- W2897299802 date "2018-10-01" @default.
- W2897299802 modified "2023-09-23" @default.
- W2897299802 title "Quantify and qualify new bone formation and osseointegration in grafted FDB block vs. particulate FDB ones" @default.
- W2897299802 doi "https://doi.org/10.1111/clr.184_13358" @default.
- W2897299802 hasPublicationYear "2018" @default.
- W2897299802 type Work @default.
- W2897299802 sameAs 2897299802 @default.
- W2897299802 citedByCount "0" @default.
- W2897299802 crossrefType "journal-article" @default.
- W2897299802 hasAuthorship W2897299802A5030154671 @default.
- W2897299802 hasAuthorship W2897299802A5039628913 @default.
- W2897299802 hasAuthorship W2897299802A5043918394 @default.
- W2897299802 hasBestOaLocation W28972998021 @default.
- W2897299802 hasConcept C101414908 @default.
- W2897299802 hasConcept C105702510 @default.
- W2897299802 hasConcept C136229726 @default.
- W2897299802 hasConcept C141071460 @default.
- W2897299802 hasConcept C160160445 @default.
- W2897299802 hasConcept C180675623 @default.
- W2897299802 hasConcept C181199279 @default.
- W2897299802 hasConcept C185592680 @default.
- W2897299802 hasConcept C192562407 @default.
- W2897299802 hasConcept C199343813 @default.
- W2897299802 hasConcept C202751555 @default.
- W2897299802 hasConcept C21547065 @default.
- W2897299802 hasConcept C2776350087 @default.
- W2897299802 hasConcept C2779918246 @default.
- W2897299802 hasConcept C2781411149 @default.
- W2897299802 hasConcept C55493867 @default.
- W2897299802 hasConcept C71315377 @default.
- W2897299802 hasConcept C71924100 @default.
- W2897299802 hasConcept C8264082 @default.
- W2897299802 hasConcept C86803240 @default.
- W2897299802 hasConceptScore W2897299802C101414908 @default.
- W2897299802 hasConceptScore W2897299802C105702510 @default.
- W2897299802 hasConceptScore W2897299802C136229726 @default.
- W2897299802 hasConceptScore W2897299802C141071460 @default.
- W2897299802 hasConceptScore W2897299802C160160445 @default.
- W2897299802 hasConceptScore W2897299802C180675623 @default.
- W2897299802 hasConceptScore W2897299802C181199279 @default.
- W2897299802 hasConceptScore W2897299802C185592680 @default.
- W2897299802 hasConceptScore W2897299802C192562407 @default.
- W2897299802 hasConceptScore W2897299802C199343813 @default.
- W2897299802 hasConceptScore W2897299802C202751555 @default.
- W2897299802 hasConceptScore W2897299802C21547065 @default.
- W2897299802 hasConceptScore W2897299802C2776350087 @default.
- W2897299802 hasConceptScore W2897299802C2779918246 @default.
- W2897299802 hasConceptScore W2897299802C2781411149 @default.
- W2897299802 hasConceptScore W2897299802C55493867 @default.
- W2897299802 hasConceptScore W2897299802C71315377 @default.
- W2897299802 hasConceptScore W2897299802C71924100 @default.
- W2897299802 hasConceptScore W2897299802C8264082 @default.
- W2897299802 hasConceptScore W2897299802C86803240 @default.
- W2897299802 hasLocation W28972998021 @default.
- W2897299802 hasLocation W28972998022 @default.
- W2897299802 hasOpenAccess W2897299802 @default.
- W2897299802 hasPrimaryLocation W28972998021 @default.
- W2897299802 hasRelatedWork W1977989088 @default.
- W2897299802 hasRelatedWork W2001241660 @default.
- W2897299802 hasRelatedWork W2002785909 @default.
- W2897299802 hasRelatedWork W2011293372 @default.
- W2897299802 hasRelatedWork W2330359217 @default.
- W2897299802 hasRelatedWork W2350475436 @default.
- W2897299802 hasRelatedWork W2370567452 @default.
- W2897299802 hasRelatedWork W2388743200 @default.
- W2897299802 hasRelatedWork W2587891170 @default.
- W2897299802 hasRelatedWork W3024684775 @default.
- W2897299802 hasVolume "29" @default.
- W2897299802 isParatext "false" @default.
- W2897299802 isRetracted "false" @default.
- W2897299802 magId "2897299802" @default.
- W2897299802 workType "article" @default.