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- W2897300482 abstract "Fagonia indica is one of the commercially vital medicinal plant species. It is well-known for biosynthesis of anticancer phenolics and flavonoids metabolites. The plant has been exploited for in vitro studies and production of vital phytochemicals, however, the synergistic effects of melatonin and lights remains to be investigated. In current study, we have evaluated the synergistic effects of melatonin and different light emitting diodes (LEDs) in callus cultures of F. indica. Both, light and melatonin play vital role in physiological and biochemical processes of plant cell. The highest Fresh weight (FW: 320 g/L) and Dry weight (DW: 20 g/L) was recorded in cultures under white LEDs. Optimum total phenolics content (11.3 μg GAE/mg), total flavonoids content (4.02 μg QAE/mg) and Free radical scavenging activity (97%) was found in cultures grown under white LED and melatonin. Furthermore, cultures maintained under white light were also found with highest levels of phenolic and flavonoids production (total phenolic production; 226.9 μg GAE/mg, Total flavonoid production; 81 μg QAE/mg) than other LED-grown cultures. However, the antioxidant enzymes; Superoxide dismutase (SOD: 0.53 nM/min/mg FW) and Peroxidase (POD:1.18 nM/min/mg FW) were found optimum in cultures grown under blue LED. The HPLC data showed that enhanced total production of metabolites was recorded in cultures under white LED (6.765 μg/mg DW) than other lights and control. The findings of this study comprehend the role of melatonin and influence of light quality on biomass accumulation and production of phytochemicals in callus cultures of F. indica." @default.
- W2897300482 created "2018-10-26" @default.
- W2897300482 creator A5016230067 @default.
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- W2897300482 creator A5058287755 @default.
- W2897300482 creator A5078930303 @default.
- W2897300482 date "2019-01-01" @default.
- W2897300482 modified "2023-09-30" @default.
- W2897300482 title "Synergistic effects of melatonin and distinct spectral lights for enhanced production of anti-cancerous compounds in callus cultures of Fagonia indica" @default.
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- W2897300482 doi "https://doi.org/10.1016/j.jphotobiol.2018.10.010" @default.
- W2897300482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30482427" @default.
- W2897300482 hasPublicationYear "2019" @default.
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