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- W2897300942 abstract "Abstract Xylazine is marketed as a veterinary drug and used for sedative and analgesic purposes; it is not approved for human use due to various side effects. In recent years, xylazine has emerged as a drug of abuse and has been associated with drug-facilitated sexual assaults. Herein, we describe, for the first time, the electrochemical study of xylazine in aqueous and organic media and proposed a quantification method using glassy carbon electrode. The simple and accurate quantification method was performed using differential pulse voltammetry. Under the optimized experimental conditions, a linear analytical curve was obtained for xylazine concentrations ranging from 0.5 to 256 μmol L−1, with an estimated detection limit of 120 nmol L−1. The proposed method was applied to determination of xylazine in pharmaceutical formulation. Furthermore, to forensic scenario, a standard addition technique on urine samples exhibited recovery values in the range of 93–103%, demonstrating the potentiality to forensic and clinical analysis of xylazine intoxication." @default.
- W2897300942 created "2018-10-26" @default.
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- W2897300942 date "2019-02-01" @default.
- W2897300942 modified "2023-10-17" @default.
- W2897300942 title "Forensic electrochemistry: Electrochemical study and quantification of xylazine in pharmaceutical and urine samples" @default.
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- W2897300942 doi "https://doi.org/10.1016/j.electacta.2018.10.120" @default.
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