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- W2897316416 abstract "The prognosis of the babies with congenital pulmonary airway malformation (CPAM) has been evaluated with CPAM volume ratio (CVR). Some lesions diminish and it is difficult to measure at late gestation, but some cases need neonatal emergency surgery. In latter case, it is better to deliver the baby at tertiary centre. We examined whether prenatal evaluation can predict the postnatal outcome. Twenty-two CPAM cases from 2012 to 2017 were included. 5 cases had a neonatal surgery (NS group), and 17 cases had an elective surgery (ES group). Prenatal condition was evaluated longitudinally with mass volume/EFW and CVR, Postnatal CT volume and the duration to the surgery were evaluated. The timing of diagnosis was not significantly different between NS group (20.43±2.18) and ES group (22.32±2.13). The volume/EFW at diagnosis was significantly higher in NS group (p=0.015: NS group 4.33±2.82, ES group 1.59±1.39). Indeed the volume/EFW at diagnosis was significantly correlated with the postnatal mass volume by CT (p<0.01, r=0.61). The cut-off value of volume/EFW at diagnosis as a prediction for neonatal operation was 0.0205 (AUC 0.85, sensitivity 0.833, specificity 0.687). There was no significant difference between the groups in CVR at diagnosis, volume/EFW or CVR at late gestation. Although 36% cases were difficult to measure the mass accurately after 34 weeks, only 1 case completely diminished after birth, and only 2 cases did not need the surgery. In fetal CPAM, the volume/EFW at diagnosis is a useful marker to predict neonatal surgery. Indeed even if the mass diminish at late gestation, most of the cases need surgery at later life." @default.
- W2897316416 created "2018-10-26" @default.
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- W2897316416 date "2018-10-01" @default.
- W2897316416 modified "2023-10-18" @default.
- W2897316416 title "OC03.04: Prenatal assessment and the prognosis in the fetuses with congenital pulmonary airway malformation" @default.
- W2897316416 doi "https://doi.org/10.1002/uog.19221" @default.
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