Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897346316> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2897346316 abstract "In this study, the effects of exogenic application of Ganoderma lucidum polysaccharide on oxidative stress and hyperlipidemia was determined in diabetics rats. The study included 60 Wistar albino rats aged 4-5 months. Rats were divided into 6 equal groups. The groups were control, Ganoderma lucidum polysaccharide, diabetic, diabetic+60 mg/kg polysaccharides, diabetic+120 mg/kg polysaccharides and diabetic+10 mg/kg polysaccharide. Diabetes was induced by intraperitoneal injection of streptozocine at the dose rate of 50 mg/kg. The rats were fed ad-libitum throughout the experiment. At the end of the study, we took some samples out of total oxidant and total antioxidant levels and measured them with the spectrophotometer; thereafter we used the auto-analyser to measure the levels of total cholesterol, triglycerides, HDL, LDL, VLDL cholesterol and pancreatic amylase. We examined the blood of diabetic fasting rats and the effect was that their glucose level was increased significantly. (p<0.05), nonetheless the dose of 60, 120 and 180 mg/kg of Ganoderma lucidum polysaccharides did not reduce the blood glucose level (p>0.05). With the diabetic rats, the dose of 60, 120 and 180 mg/kg of Ganoderma lucidum polysaccharides rides effected in the increase of serum levels of total cholesterol, triglycerides, VLDL, and HDL cholesterol levels, although it was not a significant change (p>0.05), instead, we observed a statistically significant decrease of LDL cholesterol level (p<0.05). According to this study we concluded that polysaccharides effects in the decrease of hyperlipidaemia with regard to diabetes. During the study we applied Ganoderma lucidum polysaccharides exogenously (60, 120, 180 mg/kg) and it did not affect the level of total antioxidant in diabetes significantly (p>0.05), however with a dose of 180 mg/kg the total oxidant level in pancreas and liver tissues was reduced significantly and has been considered as crucial fact. The collected data supported our view on histopathologic examination. Based on all the information, we used one type of fungus Ganoderma lucidum polysaccharides which did not influence the blood glucose level in diabetes, whereas with regard to LDL and total oxidants it played a significant role in reducing its levels." @default.
- W2897346316 created "2018-10-26" @default.
- W2897346316 creator A5040377772 @default.
- W2897346316 creator A5054144508 @default.
- W2897346316 date "2018-01-01" @default.
- W2897346316 modified "2023-10-18" @default.
- W2897346316 title "Effect of Ganoderma lucidum polysaccharides on oxidative damage in liver of STZ-diabetic rats" @default.
- W2897346316 doi "https://doi.org/10.4066/biomedicalresearch.29-18-831" @default.
- W2897346316 hasPublicationYear "2018" @default.
- W2897346316 type Work @default.
- W2897346316 sameAs 2897346316 @default.
- W2897346316 citedByCount "1" @default.
- W2897346316 countsByYear W28973463162019 @default.
- W2897346316 crossrefType "journal-article" @default.
- W2897346316 hasAuthorship W2897346316A5040377772 @default.
- W2897346316 hasAuthorship W2897346316A5054144508 @default.
- W2897346316 hasBestOaLocation W28973463161 @default.
- W2897346316 hasConcept C100817775 @default.
- W2897346316 hasConcept C126322002 @default.
- W2897346316 hasConcept C134018914 @default.
- W2897346316 hasConcept C185592680 @default.
- W2897346316 hasConcept C2776151105 @default.
- W2897346316 hasConcept C2778004101 @default.
- W2897346316 hasConcept C2778163477 @default.
- W2897346316 hasConcept C2779091943 @default.
- W2897346316 hasConcept C2779280383 @default.
- W2897346316 hasConcept C2780072125 @default.
- W2897346316 hasConcept C2780159080 @default.
- W2897346316 hasConcept C2992468417 @default.
- W2897346316 hasConcept C31903555 @default.
- W2897346316 hasConcept C55493867 @default.
- W2897346316 hasConcept C555293320 @default.
- W2897346316 hasConcept C71924100 @default.
- W2897346316 hasConcept C8243546 @default.
- W2897346316 hasConceptScore W2897346316C100817775 @default.
- W2897346316 hasConceptScore W2897346316C126322002 @default.
- W2897346316 hasConceptScore W2897346316C134018914 @default.
- W2897346316 hasConceptScore W2897346316C185592680 @default.
- W2897346316 hasConceptScore W2897346316C2776151105 @default.
- W2897346316 hasConceptScore W2897346316C2778004101 @default.
- W2897346316 hasConceptScore W2897346316C2778163477 @default.
- W2897346316 hasConceptScore W2897346316C2779091943 @default.
- W2897346316 hasConceptScore W2897346316C2779280383 @default.
- W2897346316 hasConceptScore W2897346316C2780072125 @default.
- W2897346316 hasConceptScore W2897346316C2780159080 @default.
- W2897346316 hasConceptScore W2897346316C2992468417 @default.
- W2897346316 hasConceptScore W2897346316C31903555 @default.
- W2897346316 hasConceptScore W2897346316C55493867 @default.
- W2897346316 hasConceptScore W2897346316C555293320 @default.
- W2897346316 hasConceptScore W2897346316C71924100 @default.
- W2897346316 hasConceptScore W2897346316C8243546 @default.
- W2897346316 hasIssue "18" @default.
- W2897346316 hasLocation W28973463161 @default.
- W2897346316 hasOpenAccess W2897346316 @default.
- W2897346316 hasPrimaryLocation W28973463161 @default.
- W2897346316 hasRelatedWork W2005998106 @default.
- W2897346316 hasRelatedWork W2022180711 @default.
- W2897346316 hasRelatedWork W2113363221 @default.
- W2897346316 hasRelatedWork W2118889799 @default.
- W2897346316 hasRelatedWork W2128685876 @default.
- W2897346316 hasRelatedWork W2160569095 @default.
- W2897346316 hasRelatedWork W2380317211 @default.
- W2897346316 hasRelatedWork W2418228134 @default.
- W2897346316 hasRelatedWork W2588257954 @default.
- W2897346316 hasRelatedWork W2607144198 @default.
- W2897346316 hasVolume "29" @default.
- W2897346316 isParatext "false" @default.
- W2897346316 isRetracted "false" @default.
- W2897346316 magId "2897346316" @default.
- W2897346316 workType "article" @default.