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- W2897350229 abstract "Medication nonadherence is a significant barrier in achieving seizure freedom in patients with epilepsy. There is a deficiency of data about the reasons for nonadherence in Saudi population.The aim of this study is to prove the existence of nonadherence to antiepileptic drugs (AEDs) in patients with epilepsy and identify the responsible factors.This is a prospective, cross-sectional study carried in the Department of Neurology at King Fahd Hospital of the University affiliated with Imam Abdulrahman Bin Faisal University.Patients of all ages diagnosed to have epilepsy as mentioned in their medical record and taking antiepileptic medications were interviewed using a questionnaire.Statistical analysis was performed using IBM Statistical Package for the Social Sciences version 21 (IBM Corp., Armonk, NY, USA). Statistical significance was defined as two-tailed with a P ≤ 0.05.Among 152 participants, 52.6% were male and 47.4% were female. Mean age of the patients was 28 ± 14.3 (mean ± standard deviation) years. Of 152 patients, 48.7% were found to be nonadherent to their AED therapy. The most commonly identified factor was forgetfulness. Nonadherence was significantly associated with poor seizure control (P = 0.002).Nonadherence to the AED is common among patients with epilepsy and affects seizure control adversely." @default.
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- W2897350229 date "2019-01-01" @default.
- W2897350229 modified "2023-10-01" @default.
- W2897350229 title "Nonadherence to Antiepileptic Medications: Still a Major Issue to be Addressed in the Management of Epilepsy" @default.
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- W2897350229 doi "https://doi.org/10.4103/jnrp.jnrp_136_18" @default.
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