FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897366926> ?p ?o ?g. }

• W2897366926 endingPage "773" @default.
• W2897366926 startingPage "763" @default.
• W2897366926 abstract "RNA interference shows a great strategy for biological studies; however, delivering of small interfering RNA (siRNA) remains challenging. Although several delivery vehicles, including cell-penetrating peptides, have been developed, their implementation is often restricted because of their endosomal entrapment. Herein, we report the formation of self-assembled nanostructures from rationally designed cyclic peptides and explore them for efficient delivery of functional biomacromolecules such as siRNA into mammalian cells. The newly obtained soft materials make stable complexes with siRNAs, thereby increasing their stability and deliver fluorescent labelled siRNA inside the cells as evident from confocal microscopy analysis. Flow cytometry analysis reveals that significant uptake of FAM-siRNA occurs in the presence of peptide nanostructures compared with siRNA alone. Peptide nanostructure-mediated delivery of very low concentration of siRNA causes significant knockdown of the target gene as observed at protein level by Western blot analysis, which is comparable to lipofectamine, commercially available transfection agent." @default.
• W2897366926 created "2018-10-26" @default.
• W2897366926 creator A5004454088 @default.
• W2897366926 creator A5044903753 @default.
• W2897366926 creator A5045576618 @default.
• W2897366926 creator A5085939131 @default.
• W2897366926 date "2018-10-12" @default.
• W2897366926 modified "2023-10-14" @default.
• W2897366926 title "Cyclic peptide-based nanostructures as efficient siRNA carriers" @default.
• W2897366926 cites W1881967720 @default.
• W2897366926 cites W1963673259 @default.
• W2897366926 cites W1965388827 @default.
• W2897366926 cites W1971409649 @default.
• W2897366926 cites W1973283490 @default.
• W2897366926 cites W1975875150 @default.
• W2897366926 cites W1978519286 @default.
• W2897366926 cites W1979882847 @default.
• W2897366926 cites W1986849641 @default.
• W2897366926 cites W1993190737 @default.
• W2897366926 cites W2012304333 @default.
• W2897366926 cites W2013947977 @default.
• W2897366926 cites W2032576390 @default.
• W2897366926 cites W2040831696 @default.
• W2897366926 cites W2053626384 @default.
• W2897366926 cites W2056810463 @default.
• W2897366926 cites W2066794677 @default.
• W2897366926 cites W2067599444 @default.
• W2897366926 cites W2069444054 @default.
• W2897366926 cites W2072069652 @default.
• W2897366926 cites W2073026167 @default.
• W2897366926 cites W2079335891 @default.
• W2897366926 cites W2080441595 @default.
• W2897366926 cites W2088960285 @default.
• W2897366926 cites W2099826607 @default.
• W2897366926 cites W2113972541 @default.
• W2897366926 cites W2127677388 @default.
• W2897366926 cites W2130115096 @default.
• W2897366926 cites W2130501958 @default.
• W2897366926 cites W2136420931 @default.
• W2897366926 cites W2146138017 @default.
• W2897366926 cites W2159388700 @default.
• W2897366926 cites W2166618356 @default.
• W2897366926 cites W2216033157 @default.
• W2897366926 cites W2238042787 @default.
• W2897366926 cites W2327335574 @default.
• W2897366926 cites W2410103350 @default.
• W2897366926 cites W2486387552 @default.
• W2897366926 cites W2509907629 @default.
• W2897366926 cites W2557242880 @default.
• W2897366926 cites W2609110859 @default.
• W2897366926 cites W2767571743 @default.
• W2897366926 cites W4236298298 @default.
• W2897366926 doi "https://doi.org/10.1080/21691401.2018.1511574" @default.
• W2897366926 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30311806" @default.
• W2897366926 hasPublicationYear "2018" @default.
• W2897366926 type Work @default.
• W2897366926 sameAs 2897366926 @default.
• W2897366926 citedByCount "19" @default.
• W2897366926 countsByYear W28973669262019 @default.
• W2897366926 countsByYear W28973669262020 @default.
• W2897366926 countsByYear W28973669262021 @default.
• W2897366926 countsByYear W28973669262022 @default.
• W2897366926 countsByYear W28973669262023 @default.
• W2897366926 crossrefType "journal-article" @default.
• W2897366926 hasAuthorship W2897366926A5004454088 @default.
• W2897366926 hasAuthorship W2897366926A5044903753 @default.
• W2897366926 hasAuthorship W2897366926A5045576618 @default.
• W2897366926 hasAuthorship W2897366926A5085939131 @default.
• W2897366926 hasBestOaLocation W28973669261 @default.
• W2897366926 hasConcept C102747710 @default.
• W2897366926 hasConcept C104317684 @default.
• W2897366926 hasConcept C12554922 @default.
• W2897366926 hasConcept C153911025 @default.
• W2897366926 hasConcept C166703698 @default.
• W2897366926 hasConcept C171250308 @default.
• W2897366926 hasConcept C173396325 @default.
• W2897366926 hasConcept C185592680 @default.
• W2897366926 hasConcept C192562407 @default.
• W2897366926 hasConcept C22615655 @default.
• W2897366926 hasConcept C2779178360 @default.
• W2897366926 hasConcept C2779281246 @default.
• W2897366926 hasConcept C40767141 @default.
• W2897366926 hasConcept C49923114 @default.
• W2897366926 hasConcept C54009773 @default.
• W2897366926 hasConcept C553184892 @default.
• W2897366926 hasConcept C55493867 @default.
• W2897366926 hasConcept C67705224 @default.
• W2897366926 hasConcept C79879829 @default.
• W2897366926 hasConcept C86803240 @default.
• W2897366926 hasConcept C92087593 @default.
• W2897366926 hasConcept C95444343 @default.
• W2897366926 hasConceptScore W2897366926C102747710 @default.
• W2897366926 hasConceptScore W2897366926C104317684 @default.
• W2897366926 hasConceptScore W2897366926C12554922 @default.
• W2897366926 hasConceptScore W2897366926C153911025 @default.
• W2897366926 hasConceptScore W2897366926C166703698 @default.
• W2897366926 hasConceptScore W2897366926C171250308 @default.
• W2897366926 hasConceptScore W2897366926C173396325 @default.

• next