Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897371457> ?p ?o ?g. }
- W2897371457 endingPage "144" @default.
- W2897371457 startingPage "138" @default.
- W2897371457 abstract "Background: Grindstone technique has been widely used as an efficient, consistent, more environmentally benign, solvent-free protocol for the preparation of many compounds with higher atom economy. Methods: A series of fourteen piperonal chalcone compounds were synthesized by this method and characterized by physical and spectral data (FT-IR, 1H NMR, Mass and elemental analysis). All chalcones were evaluated for their cytotoxic action against the cancer cell lines, MCF-7 and HepG2. One 2-pyridyl-substituted compound 14 with IC50 values 17.4±0.2 towards MCF-7 and 15.4±0.6µmol L-1 towards HepG2 cells. Results: The results demonstrated that the cytotoxic activity of 2-pyridyl-substituted compound shown higher activity as compared with the standard cisplatin towards HepG2 cells. Conclusion: Compound 14 showed good antioxidant activities in the DPPH test and H2O2 assay (IC50 = 17.23± 33/µg/mL and 20.17± 0.33µg/mL) when compared with the standard ascorbic acid (IC50=µg/mL 18.26 ± 0.22and 21.66± 1.06 µg/mL)." @default.
- W2897371457 created "2018-10-26" @default.
- W2897371457 creator A5003212999 @default.
- W2897371457 creator A5023941392 @default.
- W2897371457 creator A5027533361 @default.
- W2897371457 creator A5041550090 @default.
- W2897371457 creator A5062188237 @default.
- W2897371457 creator A5071846018 @default.
- W2897371457 creator A5082436804 @default.
- W2897371457 creator A5090710811 @default.
- W2897371457 date "2020-02-13" @default.
- W2897371457 modified "2023-10-17" @default.
- W2897371457 title "An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation" @default.
- W2897371457 cites W1913057096 @default.
- W2897371457 cites W1969149447 @default.
- W2897371457 cites W1984101131 @default.
- W2897371457 cites W2006447847 @default.
- W2897371457 cites W2011060238 @default.
- W2897371457 cites W2012991711 @default.
- W2897371457 cites W2034528557 @default.
- W2897371457 cites W2037427678 @default.
- W2897371457 cites W2038421986 @default.
- W2897371457 cites W2058962495 @default.
- W2897371457 cites W2064313571 @default.
- W2897371457 cites W2070822454 @default.
- W2897371457 cites W2078338300 @default.
- W2897371457 cites W2116357058 @default.
- W2897371457 cites W2148995973 @default.
- W2897371457 cites W2217142759 @default.
- W2897371457 cites W2221035395 @default.
- W2897371457 cites W2339468509 @default.
- W2897371457 cites W2347173484 @default.
- W2897371457 cites W2620871706 @default.
- W2897371457 cites W2757458863 @default.
- W2897371457 cites W828307481 @default.
- W2897371457 doi "https://doi.org/10.2174/1570180815666181016155934" @default.
- W2897371457 hasPublicationYear "2020" @default.
- W2897371457 type Work @default.
- W2897371457 sameAs 2897371457 @default.
- W2897371457 citedByCount "4" @default.
- W2897371457 countsByYear W28973714572020 @default.
- W2897371457 countsByYear W28973714572021 @default.
- W2897371457 countsByYear W28973714572023 @default.
- W2897371457 crossrefType "journal-article" @default.
- W2897371457 hasAuthorship W2897371457A5003212999 @default.
- W2897371457 hasAuthorship W2897371457A5023941392 @default.
- W2897371457 hasAuthorship W2897371457A5027533361 @default.
- W2897371457 hasAuthorship W2897371457A5041550090 @default.
- W2897371457 hasAuthorship W2897371457A5062188237 @default.
- W2897371457 hasAuthorship W2897371457A5071846018 @default.
- W2897371457 hasAuthorship W2897371457A5082436804 @default.
- W2897371457 hasAuthorship W2897371457A5090710811 @default.
- W2897371457 hasConcept C13965031 @default.
- W2897371457 hasConcept C141071460 @default.
- W2897371457 hasConcept C154317977 @default.
- W2897371457 hasConcept C178790620 @default.
- W2897371457 hasConcept C185592680 @default.
- W2897371457 hasConcept C202751555 @default.
- W2897371457 hasConcept C21951064 @default.
- W2897371457 hasConcept C2776694085 @default.
- W2897371457 hasConcept C2777752497 @default.
- W2897371457 hasConcept C2778004101 @default.
- W2897371457 hasConcept C2778239845 @default.
- W2897371457 hasConcept C2780471494 @default.
- W2897371457 hasConcept C2780764945 @default.
- W2897371457 hasConcept C2781401929 @default.
- W2897371457 hasConcept C2986274086 @default.
- W2897371457 hasConcept C31903555 @default.
- W2897371457 hasConcept C55493867 @default.
- W2897371457 hasConcept C71240020 @default.
- W2897371457 hasConcept C71924100 @default.
- W2897371457 hasConceptScore W2897371457C13965031 @default.
- W2897371457 hasConceptScore W2897371457C141071460 @default.
- W2897371457 hasConceptScore W2897371457C154317977 @default.
- W2897371457 hasConceptScore W2897371457C178790620 @default.
- W2897371457 hasConceptScore W2897371457C185592680 @default.
- W2897371457 hasConceptScore W2897371457C202751555 @default.
- W2897371457 hasConceptScore W2897371457C21951064 @default.
- W2897371457 hasConceptScore W2897371457C2776694085 @default.
- W2897371457 hasConceptScore W2897371457C2777752497 @default.
- W2897371457 hasConceptScore W2897371457C2778004101 @default.
- W2897371457 hasConceptScore W2897371457C2778239845 @default.
- W2897371457 hasConceptScore W2897371457C2780471494 @default.
- W2897371457 hasConceptScore W2897371457C2780764945 @default.
- W2897371457 hasConceptScore W2897371457C2781401929 @default.
- W2897371457 hasConceptScore W2897371457C2986274086 @default.
- W2897371457 hasConceptScore W2897371457C31903555 @default.
- W2897371457 hasConceptScore W2897371457C55493867 @default.
- W2897371457 hasConceptScore W2897371457C71240020 @default.
- W2897371457 hasConceptScore W2897371457C71924100 @default.
- W2897371457 hasIssue "2" @default.
- W2897371457 hasLocation W28973714571 @default.
- W2897371457 hasOpenAccess W2897371457 @default.
- W2897371457 hasPrimaryLocation W28973714571 @default.
- W2897371457 hasRelatedWork W1983291282 @default.
- W2897371457 hasRelatedWork W1992943367 @default.
- W2897371457 hasRelatedWork W2079904276 @default.
- W2897371457 hasRelatedWork W2085044184 @default.