FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897399005> ?p ?o ?g. }

• W2897399005 endingPage "556" @default.
• W2897399005 startingPage "556" @default.
• W2897399005 abstract "Enterovirus 71 (EV71) is the main pathogen of severe hand-foot-mouth disease (HFMD). Long non-coding RNAs (lncRNAs) are recognized as pivotal factors during the pathogenesis of viral infection. However, the critical functions of lncRNAs in EV71–host interactions have not been characterized. Here, for the first time, we performed global transcriptome analysis of lncRNA and mRNA expression profiles in EV71-infected human rhabdomyosarcoma (RD) cells and skeletal muscle of mice using second-generation sequencing. In our study, a total of 3801 novel lncRNAs were identified. In addition, 23 lncRNAs and 372 mRNAs exhibited remarkable differences in expression levels between infected and uninfected RD cells, while 104 lncRNAs and 2647 mRNAs were differentially expressed in infected skeletal muscle from neonatal mice. Comprehensive bioinformatics analysis included target gene prediction, lncRNA‑mRNA co-expression network construction, as well as gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis mainly focused on differentially-expressed genes (DEGs). Our results suggest that lncRNAs may participate in EV71 infection-induced pathogenesis through regulating immune responses, protein binding, cellular component biogenesis and metabolism. The present study provides novel insights into the functions of lncRNAs and the possible pathogenic mechanism following EV71 infection." @default.
• W2897399005 created "2018-10-26" @default.
• W2897399005 creator A5002259664 @default.
• W2897399005 creator A5012644558 @default.
• W2897399005 creator A5017590136 @default.
• W2897399005 creator A5023205295 @default.
• W2897399005 creator A5041247169 @default.
• W2897399005 creator A5056036725 @default.
• W2897399005 creator A5058395987 @default.
• W2897399005 creator A5060002817 @default.
• W2897399005 creator A5063361052 @default.
• W2897399005 creator A5063710395 @default.
• W2897399005 creator A5073803027 @default.
• W2897399005 creator A5089966579 @default.
• W2897399005 date "2018-10-11" @default.
• W2897399005 modified "2023-10-02" @default.
• W2897399005 title "Characterization of Critical Functions of Long Non-Coding RNAs and mRNAs in Rhabdomyosarcoma Cells and Mouse Skeletal Muscle Infected by Enterovirus 71 Using RNA-Seq" @default.
• W2897399005 cites W1485539953 @default.
• W2897399005 cites W1897003648 @default.
• W2897399005 cites W1980148349 @default.
• W2897399005 cites W2014201431 @default.
• W2897399005 cites W2019523362 @default.
• W2897399005 cites W2034926804 @default.
• W2897399005 cites W2047105938 @default.
• W2897399005 cites W2048113193 @default.
• W2897399005 cites W2055929468 @default.
• W2897399005 cites W2062785324 @default.
• W2897399005 cites W2075370291 @default.
• W2897399005 cites W2085220756 @default.
• W2897399005 cites W2087377443 @default.
• W2897399005 cites W2087616533 @default.
• W2897399005 cites W2091161969 @default.
• W2897399005 cites W2092409268 @default.
• W2897399005 cites W2116432038 @default.
• W2897399005 cites W2149524489 @default.
• W2897399005 cites W2153545807 @default.
• W2897399005 cites W2157399331 @default.
• W2897399005 cites W2161175100 @default.
• W2897399005 cites W2171696743 @default.
• W2897399005 cites W2176555004 @default.
• W2897399005 cites W2180674495 @default.
• W2897399005 cites W2191256284 @default.
• W2897399005 cites W2254791612 @default.
• W2897399005 cites W2282084472 @default.
• W2897399005 cites W2293799788 @default.
• W2897399005 cites W2413842675 @default.
• W2897399005 cites W2416326272 @default.
• W2897399005 cites W2514088426 @default.
• W2897399005 cites W2518171772 @default.
• W2897399005 cites W2567665210 @default.
• W2897399005 cites W2735515394 @default.
• W2897399005 cites W2737264786 @default.
• W2897399005 cites W2742762321 @default.
• W2897399005 cites W2760108484 @default.
• W2897399005 cites W2763619478 @default.
• W2897399005 cites W2776889916 @default.
• W2897399005 cites W2794356724 @default.
• W2897399005 cites W2794889151 @default.
• W2897399005 cites W2804009477 @default.
• W2897399005 cites W2892210799 @default.
• W2897399005 doi "https://doi.org/10.3390/v10100556" @default.
• W2897399005 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6213062" @default.
• W2897399005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30314355" @default.
• W2897399005 hasPublicationYear "2018" @default.
• W2897399005 type Work @default.
• W2897399005 sameAs 2897399005 @default.
• W2897399005 citedByCount "20" @default.
• W2897399005 countsByYear W28973990052019 @default.
• W2897399005 countsByYear W28973990052020 @default.
• W2897399005 countsByYear W28973990052021 @default.
• W2897399005 countsByYear W28973990052022 @default.
• W2897399005 countsByYear W28973990052023 @default.
• W2897399005 crossrefType "journal-article" @default.
• W2897399005 hasAuthorship W2897399005A5002259664 @default.
• W2897399005 hasAuthorship W2897399005A5012644558 @default.
• W2897399005 hasAuthorship W2897399005A5017590136 @default.
• W2897399005 hasAuthorship W2897399005A5023205295 @default.
• W2897399005 hasAuthorship W2897399005A5041247169 @default.
• W2897399005 hasAuthorship W2897399005A5056036725 @default.
• W2897399005 hasAuthorship W2897399005A5058395987 @default.
• W2897399005 hasAuthorship W2897399005A5060002817 @default.
• W2897399005 hasAuthorship W2897399005A5063361052 @default.
• W2897399005 hasAuthorship W2897399005A5063710395 @default.
• W2897399005 hasAuthorship W2897399005A5073803027 @default.
• W2897399005 hasAuthorship W2897399005A5089966579 @default.
• W2897399005 hasBestOaLocation W28973990051 @default.
• W2897399005 hasConcept C104317684 @default.
• W2897399005 hasConcept C105580179 @default.
• W2897399005 hasConcept C134018914 @default.
• W2897399005 hasConcept C150194340 @default.
• W2897399005 hasConcept C152724338 @default.
• W2897399005 hasConcept C162317418 @default.
• W2897399005 hasConcept C2779959927 @default.
• W2897399005 hasConcept C54355233 @default.
• W2897399005 hasConcept C62203573 @default.
• W2897399005 hasConcept C67705224 @default.
• W2897399005 hasConcept C70721500 @default.
• W2897399005 hasConcept C86803240 @default.

• next