FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897404218> ?p ?o ?g. }

• W2897404218 endingPage "229" @default.
• W2897404218 startingPage "219" @default.
• W2897404218 abstract "ObjectiveIt is unclear if anterior cruciate ligament (ACL) reconstruction can prevent the onset of degenerative changes in the knee. Previous studies were inconclusive on this subject. The aim of this study was to systematically review all studies on the effect of ACL reconstruction on articular cartilage in animals.DesignPubmed and Embase were searched to identify all original articles concerning the effect of ACL reconstruction on articular cartilage compared with both its positive (ACL transection) and negative (sham and/or non-operated) control in animals. Subsequently a Risk of bias and meta analysis was conducted based on five outcomes (gross macroscopic assessment, medical imaging, histological histochemical grading, histomophometrics and biomechanical characterization) related to articular cartilage.ResultsFrom the 19 included studies, 29 independent comparisons could be identified which underwent ACL reconstruction with an average timing of data collection of 23 weeks (range 1–104 weeks). Due to limited data availability meta-analysis could only be conducted for gross macroscopic damage. ACL reconstruction caused significant gross macroscopic damage compared with intact controls (SMD 2.0 [0.88; 3.13]). These findings were supported by individual studies reporting on histomorphometrics, histology and imaging. No significant gross macroscopic damage was found when ACL reconstruction was compared with ACL transection (SMD −0.64 [−1.85; 0.57]).ConclusionThis systematic review with an average follow up of included studies of 23 weeks (range 1–104 weeks) demonstrates that, in animals, ACL reconstruction does not protect articular cartilage from degenerative changes. The consistency of the direction of effect, provides some reassurance that the direction of effect in humans might be the same." @default.
• W2897404218 created "2018-10-26" @default.
• W2897404218 creator A5028075770 @default.
• W2897404218 creator A5057836299 @default.
• W2897404218 creator A5058865674 @default.
• W2897404218 creator A5064022439 @default.
• W2897404218 creator A5064882970 @default.
• W2897404218 date "2019-02-01" @default.
• W2897404218 modified "2023-10-06" @default.
• W2897404218 title "The protective effect of anterior cruciate ligament reconstruction on articular cartilage: a systematic review of animal studies" @default.
• W2897404218 cites W1267401870 @default.
• W2897404218 cites W1593555249 @default.
• W2897404218 cites W1918204060 @default.
• W2897404218 cites W1966133108 @default.
• W2897404218 cites W1971872860 @default.
• W2897404218 cites W1981204755 @default.
• W2897404218 cites W2000305529 @default.
• W2897404218 cites W2001509532 @default.
• W2897404218 cites W2002389157 @default.
• W2897404218 cites W2003973722 @default.
• W2897404218 cites W2010743805 @default.
• W2897404218 cites W2015769931 @default.
• W2897404218 cites W2017988726 @default.
• W2897404218 cites W2020386168 @default.
• W2897404218 cites W2024959837 @default.
• W2897404218 cites W2027251634 @default.
• W2897404218 cites W2029530232 @default.
• W2897404218 cites W2038692563 @default.
• W2897404218 cites W2039651603 @default.
• W2897404218 cites W2048629786 @default.
• W2897404218 cites W2055055298 @default.
• W2897404218 cites W2058435889 @default.
• W2897404218 cites W2058571677 @default.
• W2897404218 cites W2059103432 @default.
• W2897404218 cites W2061434619 @default.
• W2897404218 cites W2066933531 @default.
• W2897404218 cites W2067107673 @default.
• W2897404218 cites W2076046133 @default.
• W2897404218 cites W2088407177 @default.
• W2897404218 cites W2098923148 @default.
• W2897404218 cites W2100305113 @default.
• W2897404218 cites W2100534575 @default.
• W2897404218 cites W2101855157 @default.
• W2897404218 cites W2104927342 @default.
• W2897404218 cites W2107024568 @default.
• W2897404218 cites W2107328434 @default.
• W2897404218 cites W2108242700 @default.
• W2897404218 cites W2113628416 @default.
• W2897404218 cites W2118421727 @default.
• W2897404218 cites W2125626598 @default.
• W2897404218 cites W2132797493 @default.
• W2897404218 cites W2135163374 @default.
• W2897404218 cites W2136678039 @default.
• W2897404218 cites W2138029135 @default.
• W2897404218 cites W2152005950 @default.
• W2897404218 cites W2155109953 @default.
• W2897404218 cites W2157502085 @default.
• W2897404218 cites W2164074199 @default.
• W2897404218 cites W2166075773 @default.
• W2897404218 cites W2166592703 @default.
• W2897404218 cites W2231016440 @default.
• W2897404218 cites W2296176089 @default.
• W2897404218 cites W2300746289 @default.
• W2897404218 cites W2399720646 @default.
• W2897404218 cites W2519844612 @default.
• W2897404218 cites W2554463235 @default.
• W2897404218 cites W2580241481 @default.
• W2897404218 cites W2592253505 @default.
• W2897404218 cites W2596747593 @default.
• W2897404218 cites W2619740623 @default.
• W2897404218 cites W2623587252 @default.
• W2897404218 cites W2739107061 @default.
• W2897404218 cites W2747114157 @default.
• W2897404218 cites W2748776530 @default.
• W2897404218 cites W2750038994 @default.
• W2897404218 cites W2784327403 @default.
• W2897404218 cites W2892390398 @default.
• W2897404218 cites W3150342819 @default.
• W2897404218 cites W4211003135 @default.
• W2897404218 cites W784232644 @default.
• W2897404218 cites W2800751182 @default.
• W2897404218 doi "https://doi.org/10.1016/j.joca.2018.10.001" @default.
• W2897404218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30317001" @default.
• W2897404218 hasPublicationYear "2019" @default.
• W2897404218 type Work @default.
• W2897404218 sameAs 2897404218 @default.
• W2897404218 citedByCount "6" @default.
• W2897404218 countsByYear W28974042182019 @default.
• W2897404218 countsByYear W28974042182021 @default.
• W2897404218 countsByYear W28974042182022 @default.
• W2897404218 crossrefType "journal-article" @default.
• W2897404218 hasAuthorship W2897404218A5028075770 @default.
• W2897404218 hasAuthorship W2897404218A5057836299 @default.
• W2897404218 hasAuthorship W2897404218A5058865674 @default.
• W2897404218 hasAuthorship W2897404218A5064022439 @default.
• W2897404218 hasAuthorship W2897404218A5064882970 @default.
• W2897404218 hasBestOaLocation W28974042181 @default.
• W2897404218 hasConcept C105702510 @default.

• next