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• W2897405034 abstract "Dual cancer therapy is an attractive strategy that can generate synergistic effects and also reduce drug-related side effects. Here, we developed multifunctional nanocomplexes capable of remote on-demand production of hyperthermia and free radicals in response to near infrared (NIR) light irradiation To this end, thermal initiator and gold nanorods were embedded in nano-sized temperature-responsive poly(lactic acid-co-glycolic acid). In vitro studies demonstrated controllable heat and radical production from the nanocomplexes with NIR and effective eradication of CT26 colon cancer cells with our nanocomplexes. Hence, our smart nanomaterial will potentially contribute precise and effective dual cancer treatment." @default.
• W2897405034 created "2018-10-26" @default.
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• W2897405034 date "2019-01-01" @default.
• W2897405034 modified "2023-10-02" @default.
• W2897405034 title "On-demand generation of heat and free radicals for dual cancer therapy using thermal initiator- and gold nanorod-embedded PLGA nanocomplexes" @default.
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• W2897405034 doi "https://doi.org/10.1016/j.jiec.2018.09.051" @default.
• W2897405034 hasPublicationYear "2019" @default.
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