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• W2897413133 abstract "Background: Improving flap survival is essential for successful soft-tissue reconstruction. Although many methods to increase the survival of the distal flap portion have been attempted, there has been no widely adopted procedure. The authors evaluated the effect of flap preconditioning with two different modes (continuous and cyclic) of external volume expansion (pressure-controlled cupping) in a rat dorsal flap model. Methods: Thirty rats were randomly assigned to the control group and two experimental groups ( n = 10 per group). The continuous group underwent 30 minutes of preconditioning with −25 mmHg pressure once daily for 5 days. The cyclic group received 0 to −25 mmHg pressure for 30 minutes with the cyclic mode once daily for 5 days. On the day after the final preconditioning, caudally based 2 × 8-cm dorsal random-pattern flaps were raised and replaced in the native position. On postoperative day 9, the surviving flap area was evaluated. Results: The cyclic group showed the highest flap survival rate (76.02 percent), followed by the continuous and control groups (64.96 percent and 51.53 percent, respectively). All intergroup differences were statistically significant. Tissue perfusion of the entire flap showed similar results (cyclic, 87.13 percent; continuous, 66.64 percent; control, 49.32 percent). Histologic analysis showed the most increased and organized collagen production with hypertrophy of the attached muscle and vascular density in the cyclic group, followed by the continuous and control groups. Conclusion: Flap preconditioning with the cyclic mode of external volume expansion is more effective than the continuous mode in an experimental rat model." @default.
• W2897413133 created "2018-10-26" @default.
• W2897413133 creator A5031598883 @default.
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• W2897413133 date "2019-01-01" @default.
• W2897413133 modified "2023-10-17" @default.
• W2897413133 title "Flap Preconditioning with the Cyclic Mode (Triangular Waveform) of Pressure-Controlled Cupping in a Rat Model" @default.
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• W2897413133 doi "https://doi.org/10.1097/prs.0000000000005104" @default.
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