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- W289741721 abstract "This chapter discusses the cells of bone, the structures they produce, and the many hormones that influence them. Bone is considered to have two main functions, the mechanical support and protection of the body, and the maintenance of normal mineral metabolism. The control of these respective functions is often referred to as skeletal and mineral homeostasis. In the chemistry of bone, the importance of the organic matrix is being increasingly recognized, although little is yet known of the factors that control its metabolism. However, it is now realized that collagen exists in different genetic types and that disorders may arise from defects in its synthesis, posttranslational modifications, and cross-linkage. Additionally, relevant components of the minor non-collagen protein fraction of bone have been identified, that include a specific glycoprotein of plasma apparently made by the liver and incorporated into mineralizing bone. The source of bone cells has been much debated. Bone marrow contains two histogenetically distinct cell lines, the haemopoietic and the reticulo-endothelial systems." @default.
- W289741721 created "2016-06-24" @default.
- W289741721 creator A5026514791 @default.
- W289741721 date "1979-01-01" @default.
- W289741721 modified "2023-09-27" @default.
- W289741721 title "Physiology of Bone and its Control" @default.
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- W289741721 doi "https://doi.org/10.1016/b978-0-407-00122-0.50008-4" @default.
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