FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897425218> ?p ?o ?g. }

• W2897425218 endingPage "1628" @default.
• W2897425218 startingPage "1617" @default.
• W2897425218 abstract "Background Quantitative diffusion‐weighted imaging (DWI) MRI is a promising technique for cancer characterization and treatment monitoring. Knowledge of the reproducibility of DWI metrics in breast tumors is necessary to apply DWI as a clinical biomarker. Purpose To evaluate the repeatability and reproducibility of breast tumor apparent diffusion coefficient (ADC) in a multi‐institution clinical trial setting, using standardized DWI protocols and quality assurance (QA) procedures. Study Type Prospective. Subjects In all, 89 women from nine institutions undergoing neoadjuvant chemotherapy for invasive breast cancer. Field Strength/Sequence DWI was acquired before and after patient repositioning using a four b‐value, single‐shot echo‐planar sequence at 1.5T or 3.0T. Assessment A QA procedure by trained operators assessed artifacts, fat suppression, and signal‐to‐noise ratio, and determine study analyzability. Mean tumor ADC was measured via manual segmentation of the multislice tumor region referencing DWI and contrast‐enhanced images. Twenty cases were evaluated multiple times to assess intra‐ and interoperator variability. Segmentation similarity was assessed via the Sørenson–Dice similarity coefficient. Statistical Tests Repeatability and reproducibility were evaluated using within‐subject coefficient of variation (wCV), intraclass correlation coefficient (ICC), agreement index (AI), and repeatability coefficient (RC). Correlations were measured by Pearson's correlation coefficients. Results In all, 71 cases (80%) passed QA evaluation: 44 at 1.5T, 27 at 3.0T; 60 pretreatment, 11 after 3 weeks of taxane‐based treatment. ADC repeatability was excellent: wCV = 4.8% (95% confidence interval [CI] 4.0, 5.7%), ICC = 0.97 (95% CI 0.95, 0.98), AI = 0.83 (95% CI 0.76, 0.87), and RC = 0.16 * 10 −3 mm 2 /sec (95% CI 0.13, 0.19). The results were similar across field strengths and timepoint subgroups. Reproducibility was excellent: interreader ICC = 0.92 (95% CI 0.80, 0.97) and intrareader ICC = 0.91 (95% CI 0.78, 0.96). Data Conclusion Breast tumor ADC can be measured with excellent repeatability and reproducibility in a multi‐institution setting using a standardized protocol and QA procedure. Improvements to DWI image quality could reduce loss of data in clinical trials. Level of Evidence: 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2019;49:1617–1628." @default.
• W2897425218 created "2018-10-26" @default.
• W2897425218 creator A5001969147 @default.
• W2897425218 creator A5009510778 @default.
• W2897425218 creator A5010926549 @default.
• W2897425218 creator A5012847376 @default.
• W2897425218 creator A5016580708 @default.
• W2897425218 creator A5017319649 @default.
• W2897425218 creator A5023543805 @default.
• W2897425218 creator A5025334715 @default.
• W2897425218 creator A5028905467 @default.
• W2897425218 creator A5034796205 @default.
• W2897425218 creator A5038035815 @default.
• W2897425218 creator A5046435712 @default.
• W2897425218 creator A5049607541 @default.
• W2897425218 creator A5068265574 @default.
• W2897425218 creator A5072789687 @default.
• W2897425218 creator A5075239843 @default.
• W2897425218 creator A5076975841 @default.
• W2897425218 creator A5085422087 @default.
• W2897425218 creator A5088888083 @default.
• W2897425218 creator A5089422969 @default.
• W2897425218 date "2018-10-22" @default.
• W2897425218 modified "2023-10-16" @default.
• W2897425218 title "Test–retest repeatability and reproducibility of ADC measures by breast DWI: Results from the ACRIN 6698 trial" @default.
• W2897425218 cites W1977572793 @default.
• W2897425218 cites W1985847586 @default.
• W2897425218 cites W1987869189 @default.
• W2897425218 cites W1990462750 @default.
• W2897425218 cites W1994973885 @default.
• W2897425218 cites W1996212324 @default.
• W2897425218 cites W2005494948 @default.
• W2897425218 cites W202298670 @default.
• W2897425218 cites W2024314995 @default.
• W2897425218 cites W2024697399 @default.
• W2897425218 cites W2036387293 @default.
• W2897425218 cites W2038833688 @default.
• W2897425218 cites W2057794476 @default.
• W2897425218 cites W2061002999 @default.
• W2897425218 cites W2077108531 @default.
• W2897425218 cites W2080402112 @default.
• W2897425218 cites W2083717607 @default.
• W2897425218 cites W2084761689 @default.
• W2897425218 cites W2090593039 @default.
• W2897425218 cites W2099477514 @default.
• W2897425218 cites W2112522939 @default.
• W2897425218 cites W2131267314 @default.
• W2897425218 cites W2141176841 @default.
• W2897425218 cites W2147726813 @default.
• W2897425218 cites W2154448389 @default.
• W2897425218 cites W2171154227 @default.
• W2897425218 cites W2182711918 @default.
• W2897425218 cites W2204989306 @default.
• W2897425218 cites W2234347943 @default.
• W2897425218 cites W2511258052 @default.
• W2897425218 cites W2515883474 @default.
• W2897425218 cites W2528833166 @default.
• W2897425218 cites W2711255076 @default.
• W2897425218 cites W2791561970 @default.
• W2897425218 cites W2890317046 @default.
• W2897425218 cites W4253228824 @default.
• W2897425218 doi "https://doi.org/10.1002/jmri.26539" @default.
• W2897425218 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6524146" @default.
• W2897425218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30350329" @default.
• W2897425218 hasPublicationYear "2018" @default.
• W2897425218 type Work @default.
• W2897425218 sameAs 2897425218 @default.
• W2897425218 citedByCount "65" @default.
• W2897425218 countsByYear W28974252182019 @default.
• W2897425218 countsByYear W28974252182020 @default.
• W2897425218 countsByYear W28974252182021 @default.
• W2897425218 countsByYear W28974252182022 @default.
• W2897425218 countsByYear W28974252182023 @default.
• W2897425218 crossrefType "journal-article" @default.
• W2897425218 hasAuthorship W2897425218A5001969147 @default.
• W2897425218 hasAuthorship W2897425218A5009510778 @default.
• W2897425218 hasAuthorship W2897425218A5010926549 @default.
• W2897425218 hasAuthorship W2897425218A5012847376 @default.
• W2897425218 hasAuthorship W2897425218A5016580708 @default.
• W2897425218 hasAuthorship W2897425218A5017319649 @default.
• W2897425218 hasAuthorship W2897425218A5023543805 @default.
• W2897425218 hasAuthorship W2897425218A5025334715 @default.
• W2897425218 hasAuthorship W2897425218A5028905467 @default.
• W2897425218 hasAuthorship W2897425218A5034796205 @default.
• W2897425218 hasAuthorship W2897425218A5038035815 @default.
• W2897425218 hasAuthorship W2897425218A5046435712 @default.
• W2897425218 hasAuthorship W2897425218A5049607541 @default.
• W2897425218 hasAuthorship W2897425218A5068265574 @default.
• W2897425218 hasAuthorship W2897425218A5072789687 @default.
• W2897425218 hasAuthorship W2897425218A5075239843 @default.
• W2897425218 hasAuthorship W2897425218A5076975841 @default.
• W2897425218 hasAuthorship W2897425218A5085422087 @default.
• W2897425218 hasAuthorship W2897425218A5088888083 @default.
• W2897425218 hasAuthorship W2897425218A5089422969 @default.
• W2897425218 hasBestOaLocation W28974252182 @default.
• W2897425218 hasConcept C104709138 @default.
• W2897425218 hasConcept C105795698 @default.
• W2897425218 hasConcept C121608353 @default.

• next