Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897445846> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2897445846 abstract "Background and Aim: Arterial duct in term infants is closed 96 h after birth in normal conditions. In some cases, especially in preterm infants, this duct is not closed after birth, which is called patent ductus arteriosus (PDA). This disease, if left untreated, leads to depressed respiratory capacity and shunt in preterm infants. The aim of this study was to compare the effect of oral acetaminophen and ibuprofen on PDA closure in preterm infants. Materials and Methods: In this clinical trial, 50 infants with a gestational age of < 37 weeks with PDA, confirmed by echocardiography and clinical symptoms, were selected and randomly divided into two groups of 25. One group was orally given acetaminophen at 10 mg/kg body weight (BW) every 6 h for 72 h, and another group received ibuprofen at 10 mg/kg BW on the 1st day and then 5 mg/kg on the 2nd and 3rd days. Before and after the intervention, infants were examined for possible side effects using echocardiography. Results: According to the results before and after the intervention, the PDA diameter was not statistically significant difference between the two treatment groups (P = 0.328 and P = 0.602). Frequency and percentage of the closure of PDA in acetaminophen group were 23 (92%) and in the ibuprofen group 22 (88%) with no statistically significant difference (P = 1.000). The mean levels of blood urea nitrogen, creatinine, and aspartate aminotransferase were not significantly different between the two groups; however, the mean of alanine aminotransferase was higher in the acetaminophen group (P < 0.05). Urine output was normal in both groups; however, the frequency of gastrointestinal complications was higher in the ibuprofen group than in the acetaminophen group (P < 0.05). Conclusion: The results of this study indicate better or equal efficacy of acetaminophen in comparison to ibuprofen to close PDA." @default.
- W2897445846 created "2018-10-26" @default.
- W2897445846 creator A5015868298 @default.
- W2897445846 creator A5030704807 @default.
- W2897445846 creator A5040259700 @default.
- W2897445846 creator A5061689664 @default.
- W2897445846 creator A5071987210 @default.
- W2897445846 date "2018-01-01" @default.
- W2897445846 modified "2023-09-27" @default.
- W2897445846 title "Comparison of the effect of oral acetaminophen and ibuprofen on patent ductus arteriosus closure in premature infants referred to hajar hospital in Shahrekord in 2016-2017" @default.
- W2897445846 doi "https://doi.org/10.4103/jcn.jcn_47_18" @default.
- W2897445846 hasPublicationYear "2018" @default.
- W2897445846 type Work @default.
- W2897445846 sameAs 2897445846 @default.
- W2897445846 citedByCount "8" @default.
- W2897445846 countsByYear W28974458462020 @default.
- W2897445846 countsByYear W28974458462021 @default.
- W2897445846 countsByYear W28974458462022 @default.
- W2897445846 countsByYear W28974458462023 @default.
- W2897445846 crossrefType "journal-article" @default.
- W2897445846 hasAuthorship W2897445846A5015868298 @default.
- W2897445846 hasAuthorship W2897445846A5030704807 @default.
- W2897445846 hasAuthorship W2897445846A5040259700 @default.
- W2897445846 hasAuthorship W2897445846A5061689664 @default.
- W2897445846 hasAuthorship W2897445846A5071987210 @default.
- W2897445846 hasConcept C126322002 @default.
- W2897445846 hasConcept C2778176769 @default.
- W2897445846 hasConcept C2778376644 @default.
- W2897445846 hasConcept C2778722691 @default.
- W2897445846 hasConcept C2779234561 @default.
- W2897445846 hasConcept C2779944601 @default.
- W2897445846 hasConcept C2780306776 @default.
- W2897445846 hasConcept C2781236024 @default.
- W2897445846 hasConcept C42219234 @default.
- W2897445846 hasConcept C54355233 @default.
- W2897445846 hasConcept C66322754 @default.
- W2897445846 hasConcept C71924100 @default.
- W2897445846 hasConcept C86803240 @default.
- W2897445846 hasConcept C90924648 @default.
- W2897445846 hasConcept C98274493 @default.
- W2897445846 hasConceptScore W2897445846C126322002 @default.
- W2897445846 hasConceptScore W2897445846C2778176769 @default.
- W2897445846 hasConceptScore W2897445846C2778376644 @default.
- W2897445846 hasConceptScore W2897445846C2778722691 @default.
- W2897445846 hasConceptScore W2897445846C2779234561 @default.
- W2897445846 hasConceptScore W2897445846C2779944601 @default.
- W2897445846 hasConceptScore W2897445846C2780306776 @default.
- W2897445846 hasConceptScore W2897445846C2781236024 @default.
- W2897445846 hasConceptScore W2897445846C42219234 @default.
- W2897445846 hasConceptScore W2897445846C54355233 @default.
- W2897445846 hasConceptScore W2897445846C66322754 @default.
- W2897445846 hasConceptScore W2897445846C71924100 @default.
- W2897445846 hasConceptScore W2897445846C86803240 @default.
- W2897445846 hasConceptScore W2897445846C90924648 @default.
- W2897445846 hasConceptScore W2897445846C98274493 @default.
- W2897445846 hasLocation W28974458461 @default.
- W2897445846 hasOpenAccess W2897445846 @default.
- W2897445846 hasPrimaryLocation W28974458461 @default.
- W2897445846 hasRelatedWork W177019059 @default.
- W2897445846 hasRelatedWork W2006817615 @default.
- W2897445846 hasRelatedWork W2016586083 @default.
- W2897445846 hasRelatedWork W2020896435 @default.
- W2897445846 hasRelatedWork W2021745600 @default.
- W2897445846 hasRelatedWork W2051846803 @default.
- W2897445846 hasRelatedWork W2082605022 @default.
- W2897445846 hasRelatedWork W2086605257 @default.
- W2897445846 hasRelatedWork W2136467674 @default.
- W2897445846 hasRelatedWork W2370130863 @default.
- W2897445846 hasRelatedWork W2409727952 @default.
- W2897445846 hasRelatedWork W2554963505 @default.
- W2897445846 hasRelatedWork W2595074754 @default.
- W2897445846 hasRelatedWork W2604274554 @default.
- W2897445846 hasRelatedWork W2730212004 @default.
- W2897445846 hasRelatedWork W2994348686 @default.
- W2897445846 hasRelatedWork W3031074363 @default.
- W2897445846 hasRelatedWork W3032586074 @default.
- W2897445846 hasRelatedWork W3121603404 @default.
- W2897445846 hasRelatedWork W161126530 @default.
- W2897445846 isParatext "false" @default.
- W2897445846 isRetracted "false" @default.
- W2897445846 magId "2897445846" @default.
- W2897445846 workType "article" @default.