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• W2897466929 abstract "AIM OF THE STUDY: The present study was undertaken to investigate the visual and brainstem auditory functions in Migraine patients. MATERIALS AND METHODS: The subjects were recruited from Outpatient Clinic of Department of Neuromedicine, Thanjavur Medical College & Hospital, Thanjavur based on International Headache Society classification for Migraine. Subjects with history suggestive of other types of headache, TTH, cluster headache, sinusitis and subjects with Visual field defects, Auditory deficits are excluded from the study. Forty subjects (16 with Aura & 24 cases – Migraine without aura) in the mean age group of 19 to 52 yrs & forty age / sex matched controls with no history of Headache were selected for the study. Informed written consent was obtained from the subject. Ethical committee approval was obtained from the Institution before commencing the study. A detailed history of Headache duration, frequency and history suggestive of aura and history to rule out other types of headache were noted. Ophthalmologic examination was done to determine visual acuity, Field of Vision, extraocular movements and pupillary diameter. The results were analysed statistically using student „t‟ test. RESULTS:There was significant prolongation of P100 & N145 latency (p<0.05) in both Migraine with aura and without aura compared with controls. BAEP recording shows significant prolongation of latency of Wave I, III & V and the Interpeak latency I-III, III-V & I-V in Migraine with aura. In Migraine without aura, there was significant prolongation of Wave I, III & V and only III-V IPL & I-V IPL. (p<0.05). CONCLUSION:The present study results show that there is involvement of the central nervous system Visual pathway and the Brainstem in Migraine patients. The Migraine patients show prolongation of latency in Electrophysiological studies.Migraine patients with aura and without aura show significant prolongation of P100, N145 Latency with no change in P100 amplitude and in BAEP the latencies of waves I , III & V and the IPLs I-III , III- V & I-V are prolonged. These findings suggest there is defect in the central processing of visual function and BAEP alterations suggest involvement of Brainstem structures during Migraine attack.Thus, VEP and Auditory brainstem evoked responses are considered as useful, non-invasive, reliable & diagnostic techniques for better understanding the Neurophysiological processes involved in Migraine patients which aid in the selection of adequate, effective treatment in Migraine subjects.However, further studies are needed to compare the duration of the disease with the changes in the Electrophysiological study and to explain the role of Neuromodulatory centers in the brainstem in pathophysiology of Migraine. Then, the role of pattern reversal check size on VEP parameters in Migraine patients and lack of habituation during prolonged stimulation should be evaluated." @default.
• W2897466929 created "2018-10-26" @default.
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• W2897466929 date "2015-04-01" @default.
• W2897466929 modified "2023-09-27" @default.
• W2897466929 title "Evaluation of Visual Evoked Potential and Brainstem Auditory Evoked Potential in Migraine" @default.
• W2897466929 hasPublicationYear "2015" @default.
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