FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897480305> ?p ?o ?g. }

• W2897480305 endingPage "e0205257" @default.
• W2897480305 startingPage "e0205257" @default.
• W2897480305 abstract "Previous reports of lung function in cystic fibrosis (CF) patients with liver disease have shown worse, similar, or even better forced expiratory volume in 1 second (FEV1), compared to CF patients without liver disease. Varying definitions of CF liver disease likely contribute to these inconsistent relationships reported between CF lung function and liver disease. We retrospectively evaluated spirometric data in 179 subjects (62% male; 58% Phe508del homozygous) with severe CF liver disease (CFLD; defined by presence of portal hypertension due to cirrhosis). FEV1 values were referenced to both a normal population (FEV1% predicted) and CF population (CF-specific FEV1 percentile). We utilized a linear mixed model with repeated measures to assess changes in lung function (before and after diagnosis of CFLD), relative to both the normal and CF populations. At diagnosis of CFLD, the mean FEV1 was 81% predicted, or at the 53rd percentile referenced to CF patients without CFLD. There was a significant difference in post-CFLD slope compared to pre-CFLD slope (post-pre) using FEV1% predicted (-1.94, p-value < 0.0001). However, there was insignificant evidence of this difference using the CF-specific FEV1 percentile measure (-0.99, p-value = 0.1268). Although FEV1% predicted values declined in patients following CFLD diagnosis, there was not significant evidence of lung function decline in CF-specific FEV1 percentiles. Thus, the observed study cohort indicates diagnosis of severe CFLD was not associated with worsened CF lung disease when compared to a large CF reference population." @default.
• W2897480305 created "2018-10-26" @default.
• W2897480305 creator A5004168921 @default.
• W2897480305 creator A5007186704 @default.
• W2897480305 creator A5008740162 @default.
• W2897480305 creator A5022856393 @default.
• W2897480305 creator A5025317516 @default.
• W2897480305 creator A5043283805 @default.
• W2897480305 creator A5055982974 @default.
• W2897480305 creator A5076474764 @default.
• W2897480305 creator A5086737230 @default.
• W2897480305 date "2018-10-11" @default.
• W2897480305 modified "2023-10-17" @default.
• W2897480305 title "Analysis of a large cohort of cystic fibrosis patients with severe liver disease indicates lung function decline does not significantly differ from that of the general cystic fibrosis population" @default.
• W2897480305 cites W1630615775 @default.
• W2897480305 cites W1919903996 @default.
• W2897480305 cites W1966052078 @default.
• W2897480305 cites W1976148325 @default.
• W2897480305 cites W1981568260 @default.
• W2897480305 cites W1989143325 @default.
• W2897480305 cites W1993309320 @default.
• W2897480305 cites W2031242047 @default.
• W2897480305 cites W2062552675 @default.
• W2897480305 cites W2072036660 @default.
• W2897480305 cites W2082353409 @default.
• W2897480305 cites W2085360552 @default.
• W2897480305 cites W2086267380 @default.
• W2897480305 cites W2092368009 @default.
• W2897480305 cites W2118155123 @default.
• W2897480305 cites W2120478186 @default.
• W2897480305 cites W2122739791 @default.
• W2897480305 cites W2138459782 @default.
• W2897480305 cites W2327675250 @default.
• W2897480305 cites W2337925307 @default.
• W2897480305 cites W46027753 @default.
• W2897480305 doi "https://doi.org/10.1371/journal.pone.0205257" @default.
• W2897480305 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6181334" @default.
• W2897480305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30307979" @default.
• W2897480305 hasPublicationYear "2018" @default.
• W2897480305 type Work @default.
• W2897480305 sameAs 2897480305 @default.
• W2897480305 citedByCount "16" @default.
• W2897480305 countsByYear W28974803052019 @default.
• W2897480305 countsByYear W28974803052020 @default.
• W2897480305 countsByYear W28974803052021 @default.
• W2897480305 countsByYear W28974803052022 @default.
• W2897480305 countsByYear W28974803052023 @default.
• W2897480305 crossrefType "journal-article" @default.
• W2897480305 hasAuthorship W2897480305A5004168921 @default.
• W2897480305 hasAuthorship W2897480305A5007186704 @default.
• W2897480305 hasAuthorship W2897480305A5008740162 @default.
• W2897480305 hasAuthorship W2897480305A5022856393 @default.
• W2897480305 hasAuthorship W2897480305A5025317516 @default.
• W2897480305 hasAuthorship W2897480305A5043283805 @default.
• W2897480305 hasAuthorship W2897480305A5055982974 @default.
• W2897480305 hasAuthorship W2897480305A5076474764 @default.
• W2897480305 hasAuthorship W2897480305A5086737230 @default.
• W2897480305 hasBestOaLocation W28974803051 @default.
• W2897480305 hasConcept C105795698 @default.
• W2897480305 hasConcept C122048520 @default.
• W2897480305 hasConcept C126322002 @default.
• W2897480305 hasConcept C165637977 @default.
• W2897480305 hasConcept C2776938444 @default.
• W2897480305 hasConcept C2777075537 @default.
• W2897480305 hasConcept C2777214474 @default.
• W2897480305 hasConcept C2777714996 @default.
• W2897480305 hasConcept C2908647359 @default.
• W2897480305 hasConcept C3018587741 @default.
• W2897480305 hasConcept C33923547 @default.
• W2897480305 hasConcept C55520419 @default.
• W2897480305 hasConcept C71924100 @default.
• W2897480305 hasConcept C72563966 @default.
• W2897480305 hasConcept C75603125 @default.
• W2897480305 hasConcept C90924648 @default.
• W2897480305 hasConcept C99454951 @default.
• W2897480305 hasConceptScore W2897480305C105795698 @default.
• W2897480305 hasConceptScore W2897480305C122048520 @default.
• W2897480305 hasConceptScore W2897480305C126322002 @default.
• W2897480305 hasConceptScore W2897480305C165637977 @default.
• W2897480305 hasConceptScore W2897480305C2776938444 @default.
• W2897480305 hasConceptScore W2897480305C2777075537 @default.
• W2897480305 hasConceptScore W2897480305C2777214474 @default.
• W2897480305 hasConceptScore W2897480305C2777714996 @default.
• W2897480305 hasConceptScore W2897480305C2908647359 @default.
• W2897480305 hasConceptScore W2897480305C3018587741 @default.
• W2897480305 hasConceptScore W2897480305C33923547 @default.
• W2897480305 hasConceptScore W2897480305C55520419 @default.
• W2897480305 hasConceptScore W2897480305C71924100 @default.
• W2897480305 hasConceptScore W2897480305C72563966 @default.
• W2897480305 hasConceptScore W2897480305C75603125 @default.
• W2897480305 hasConceptScore W2897480305C90924648 @default.
• W2897480305 hasConceptScore W2897480305C99454951 @default.
• W2897480305 hasFunder F4320306168 @default.
• W2897480305 hasFunder F4320337357 @default.
• W2897480305 hasIssue "10" @default.
• W2897480305 hasLocation W28974803051 @default.
• W2897480305 hasLocation W28974803052 @default.
• W2897480305 hasLocation W28974803053 @default.

• next