Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897512968> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W2897512968 abstract "Objective To observe the effects of thalamus on basal ganglia information integration and relay during the exhaustive exercise, and thus to reveal the possible mechanism underlying exercise induced central fatigue.
 Methods 8 weeks old male Wistar rats were used in the experiment. By using local field potentials recording technique, the dynamic changes of neural activity in rats ventrolateralthalamus (VL) were observed during the exhaustive exercise. The changes of NR2B and GABAAa-1 receptor expression level in rats VL before , immediately after and 90 min after exhaustive exercise were also observed.
 Results The changes of neural activity in rats VL demonstrated obvious phasic features. During automatic exercise phase, the frequency of neural activity increased, the amplitude decreased, activity of α wave increased significantly (P<0.05), the power spectrum gravity frequency increased significantly (P<0.05), these changes indicate the increased neuronal excitability. During early fatigue and exhaustion phases, the frequency of neural activity decreased, the amplitude increased, activity of δ and θ wave increased significantly (P<0.05). The power spectrum gravity frequency decreased significantly (P<0.05), this indicates the decreased neuronal excitability. The expression of GABAAa-1 receptors increased significantly (P<0.05) at timepoint of exhaustion and 90min after exhaustion compared with that of rest phase.
 Conclusions As the relaying nucleus of ‘basal ganglia- thalamus-cortex’ pathway, changes of neural activity in VL is one of the important factors inducing development of fatigue and decrease of exercise performance. Changes of GABAAa-1 receptor expression may be one of the possible mechanisms leading to the change of neuronal excitability in VL.
" @default.
- W2897512968 created "2018-10-26" @default.
- W2897512968 creator A5087116548 @default.
- W2897512968 date "2018-10-04" @default.
- W2897512968 modified "2023-09-27" @default.
- W2897512968 title "PO-253 Study on the effects of thalamus on basal ganglia information integration and relay during the exhaustive exercise" @default.
- W2897512968 doi "https://doi.org/10.14428/ebr.v1i5.11013" @default.
- W2897512968 hasPublicationYear "2018" @default.
- W2897512968 type Work @default.
- W2897512968 sameAs 2897512968 @default.
- W2897512968 citedByCount "0" @default.
- W2897512968 crossrefType "journal-article" @default.
- W2897512968 hasAuthorship W2897512968A5087116548 @default.
- W2897512968 hasBestOaLocation W28975129681 @default.
- W2897512968 hasConcept C126322002 @default.
- W2897512968 hasConcept C134018914 @default.
- W2897512968 hasConcept C169760540 @default.
- W2897512968 hasConcept C185592680 @default.
- W2897512968 hasConcept C2778024521 @default.
- W2897512968 hasConcept C2778187257 @default.
- W2897512968 hasConcept C2779246727 @default.
- W2897512968 hasConcept C2779306644 @default.
- W2897512968 hasConcept C529278444 @default.
- W2897512968 hasConcept C71924100 @default.
- W2897512968 hasConcept C74254510 @default.
- W2897512968 hasConcept C86803240 @default.
- W2897512968 hasConceptScore W2897512968C126322002 @default.
- W2897512968 hasConceptScore W2897512968C134018914 @default.
- W2897512968 hasConceptScore W2897512968C169760540 @default.
- W2897512968 hasConceptScore W2897512968C185592680 @default.
- W2897512968 hasConceptScore W2897512968C2778024521 @default.
- W2897512968 hasConceptScore W2897512968C2778187257 @default.
- W2897512968 hasConceptScore W2897512968C2779246727 @default.
- W2897512968 hasConceptScore W2897512968C2779306644 @default.
- W2897512968 hasConceptScore W2897512968C529278444 @default.
- W2897512968 hasConceptScore W2897512968C71924100 @default.
- W2897512968 hasConceptScore W2897512968C74254510 @default.
- W2897512968 hasConceptScore W2897512968C86803240 @default.
- W2897512968 hasLocation W28975129681 @default.
- W2897512968 hasOpenAccess W2897512968 @default.
- W2897512968 hasPrimaryLocation W28975129681 @default.
- W2897512968 hasRelatedWork W1232882377 @default.
- W2897512968 hasRelatedWork W1589858513 @default.
- W2897512968 hasRelatedWork W1604110764 @default.
- W2897512968 hasRelatedWork W1986361307 @default.
- W2897512968 hasRelatedWork W2054625530 @default.
- W2897512968 hasRelatedWork W2081428007 @default.
- W2897512968 hasRelatedWork W2730678375 @default.
- W2897512968 hasRelatedWork W2764159098 @default.
- W2897512968 hasRelatedWork W4226232268 @default.
- W2897512968 hasRelatedWork W181570832 @default.
- W2897512968 isParatext "false" @default.
- W2897512968 isRetracted "false" @default.
- W2897512968 magId "2897512968" @default.
- W2897512968 workType "article" @default.