FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897516530> ?p ?o ?g. }

• W2897516530 endingPage "98" @default.
• W2897516530 startingPage "87" @default.
• W2897516530 abstract "Despite improvements in graft survival, solid organ transplantation is still associated with considerable infection induced morbidity and mortality. If we were able to show that serious infection risk was associated with excessive suppression of immune capacity, we would be justified in personalizing the extent of immunosuppression by carefully monitored reduction to see if we can improve immune compromize without increasing the risk of rejection. Reliable biomarkers are needed to identify this patients at an increased risk of infection. This review focuses on the currently available evidence in solid organ transplant recipients for immune non-pathogen specific biomarkers to predict severe infections with the susceptibility to particular pathogens according to the component of the immune system that is suppressed. This review is categorized into immune biomarkers representative of the humoral, cellular, phagocytic, natural killer cell and complement system. Biomarkers humoral and cellular systems of the that have demonstrated an association with infections include immunoglobulins, lymphocyte number, lymphocyte subsets, intracellular concentrations of adenosine triphosphate in stimulated CD4+ cells and soluble CD30. Biomarkers of the innate immune system that have demonstrated an association with infections include natural killer cell numbers, complement and mannose binding lectin. Emerging evidence shows that quantification of viral nucleic acid (such as Epstein Barr Virus) can act as a biomarker to predict all-cause infections. Studies that show the most promise are those in which several immune biomarkers are assessed in combination. Ongoing research is required to validate non-pathogen specific immune biomarkers in multi-centre studies using standardized study designs." @default.
• W2897516530 created "2018-10-26" @default.
• W2897516530 creator A5012696609 @default.
• W2897516530 creator A5047622715 @default.
• W2897516530 creator A5051556702 @default.
• W2897516530 date "2019-04-01" @default.
• W2897516530 modified "2023-10-18" @default.
• W2897516530 title "Can immune biomarkers predict infections in solid organ transplant recipients? A review of current evidence" @default.
• W2897516530 cites W1058319730 @default.
• W2897516530 cites W1491970318 @default.
• W2897516530 cites W1528759359 @default.
• W2897516530 cites W1546414403 @default.
• W2897516530 cites W1551712572 @default.
• W2897516530 cites W1582717102 @default.
• W2897516530 cites W1620859194 @default.
• W2897516530 cites W1670276489 @default.
• W2897516530 cites W1950038263 @default.
• W2897516530 cites W1955294545 @default.
• W2897516530 cites W1964296760 @default.
• W2897516530 cites W1964431182 @default.
• W2897516530 cites W1966642068 @default.
• W2897516530 cites W1972836054 @default.
• W2897516530 cites W1972969392 @default.
• W2897516530 cites W1973178613 @default.
• W2897516530 cites W1975021833 @default.
• W2897516530 cites W1979356356 @default.
• W2897516530 cites W1980167770 @default.
• W2897516530 cites W1980268652 @default.
• W2897516530 cites W1981552711 @default.
• W2897516530 cites W1984856779 @default.
• W2897516530 cites W1985877668 @default.
• W2897516530 cites W1986646934 @default.
• W2897516530 cites W1987191562 @default.
• W2897516530 cites W1991394425 @default.
• W2897516530 cites W1995271651 @default.
• W2897516530 cites W2000115037 @default.
• W2897516530 cites W2000604792 @default.
• W2897516530 cites W2001824115 @default.
• W2897516530 cites W2004922758 @default.
• W2897516530 cites W2005675237 @default.
• W2897516530 cites W2008553480 @default.
• W2897516530 cites W2010256207 @default.
• W2897516530 cites W2012991226 @default.
• W2897516530 cites W2018311806 @default.
• W2897516530 cites W2021665832 @default.
• W2897516530 cites W2023148106 @default.
• W2897516530 cites W2024509894 @default.
• W2897516530 cites W2024911372 @default.
• W2897516530 cites W2030537110 @default.
• W2897516530 cites W2036824357 @default.
• W2897516530 cites W2037705078 @default.
• W2897516530 cites W2037736267 @default.
• W2897516530 cites W2044394603 @default.
• W2897516530 cites W2046462591 @default.
• W2897516530 cites W2048980247 @default.
• W2897516530 cites W2049284289 @default.
• W2897516530 cites W2050752231 @default.
• W2897516530 cites W2054334209 @default.
• W2897516530 cites W2054505762 @default.
• W2897516530 cites W2056597276 @default.
• W2897516530 cites W2058419095 @default.
• W2897516530 cites W2060018629 @default.
• W2897516530 cites W2060026599 @default.
• W2897516530 cites W2061891693 @default.
• W2897516530 cites W2062014766 @default.
• W2897516530 cites W2064130337 @default.
• W2897516530 cites W2070103589 @default.
• W2897516530 cites W2071058095 @default.
• W2897516530 cites W2073762826 @default.
• W2897516530 cites W2073931496 @default.
• W2897516530 cites W2074995648 @default.
• W2897516530 cites W2079672406 @default.
• W2897516530 cites W2083289662 @default.
• W2897516530 cites W2085260657 @default.
• W2897516530 cites W2085325953 @default.
• W2897516530 cites W2089310747 @default.
• W2897516530 cites W2089317634 @default.
• W2897516530 cites W2091465645 @default.
• W2897516530 cites W2093449253 @default.
• W2897516530 cites W2096104385 @default.
• W2897516530 cites W2097024048 @default.
• W2897516530 cites W2101492251 @default.
• W2897516530 cites W2101893870 @default.
• W2897516530 cites W2103742860 @default.
• W2897516530 cites W2104034287 @default.
• W2897516530 cites W2104145538 @default.
• W2897516530 cites W2108522659 @default.
• W2897516530 cites W2111299712 @default.
• W2897516530 cites W2112430000 @default.
• W2897516530 cites W2118431332 @default.
• W2897516530 cites W2121470678 @default.
• W2897516530 cites W2122303968 @default.
• W2897516530 cites W2124791110 @default.
• W2897516530 cites W2125317769 @default.
• W2897516530 cites W2126368931 @default.
• W2897516530 cites W2136422032 @default.
• W2897516530 cites W2139644163 @default.
• W2897516530 cites W2144607464 @default.

• next