Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897518440> ?p ?o ?g. }
- W2897518440 abstract "Responsible for up to 30,000 deaths annually, leishmaniasis is a complex spectrum of diseases endemic in 97 countries around the globe. Disease control relies heavily on the early diagnosis and treatment of the active cases (relevant for anthroponotic disease), although it is widely accepted that a prophylactic vaccine for human leishmaniasis is the way to achieve the successful elimination of human disease (taking in consideration the vast list of non-human reservoirs that enable the perpetuation of parasites all around the globe). The notion that infection leads to strong and long-lasting immunity against leishmaniasis supports vaccination as an achievable goal. However, and in spite of the different candidates tested along the years, till date, we still do not have an approved vaccine for humans. In this chapter, we will explore the last advances made in the field of vaccines against Leishmania without forgetting the historical perspective, essential to the understanding of the road already undergone. We will then discuss the correlates of disease and protection, still neither consensual nor definitive, as well as the issue of pre-clinical to clinical translation. The complete understanding of these issues will be essential for the approval of a successful vaccine for human leishmaniasis." @default.
- W2897518440 created "2018-10-26" @default.
- W2897518440 creator A5039135218 @default.
- W2897518440 creator A5059902077 @default.
- W2897518440 creator A5080872827 @default.
- W2897518440 date "2018-10-10" @default.
- W2897518440 modified "2023-10-18" @default.
- W2897518440 title "Vaccines for Human Leishmaniasis: Where Do We Stand and What Is Still Missing?" @default.
- W2897518440 cites W1202877721 @default.
- W2897518440 cites W1578972684 @default.
- W2897518440 cites W1607721371 @default.
- W2897518440 cites W1609492724 @default.
- W2897518440 cites W1657991880 @default.
- W2897518440 cites W1809811420 @default.
- W2897518440 cites W1832243663 @default.
- W2897518440 cites W1898151446 @default.
- W2897518440 cites W1899441152 @default.
- W2897518440 cites W1925706971 @default.
- W2897518440 cites W1942374184 @default.
- W2897518440 cites W1966362727 @default.
- W2897518440 cites W1967729898 @default.
- W2897518440 cites W1969300285 @default.
- W2897518440 cites W1971413150 @default.
- W2897518440 cites W1972018312 @default.
- W2897518440 cites W1973142062 @default.
- W2897518440 cites W1973291118 @default.
- W2897518440 cites W1983138474 @default.
- W2897518440 cites W1984776625 @default.
- W2897518440 cites W1988721092 @default.
- W2897518440 cites W1991263982 @default.
- W2897518440 cites W1992052942 @default.
- W2897518440 cites W1993160240 @default.
- W2897518440 cites W1993518869 @default.
- W2897518440 cites W1994712388 @default.
- W2897518440 cites W1995127073 @default.
- W2897518440 cites W1996935780 @default.
- W2897518440 cites W2000052617 @default.
- W2897518440 cites W2000990824 @default.
- W2897518440 cites W2002204067 @default.
- W2897518440 cites W2002678042 @default.
- W2897518440 cites W2007253465 @default.
- W2897518440 cites W2009751199 @default.
- W2897518440 cites W2012528630 @default.
- W2897518440 cites W2014050422 @default.
- W2897518440 cites W2017789152 @default.
- W2897518440 cites W2019822340 @default.
- W2897518440 cites W2022113931 @default.
- W2897518440 cites W2022333100 @default.
- W2897518440 cites W2025257704 @default.
- W2897518440 cites W2026487341 @default.
- W2897518440 cites W2026685638 @default.
- W2897518440 cites W2027114230 @default.
- W2897518440 cites W2027210355 @default.
- W2897518440 cites W2028241711 @default.
- W2897518440 cites W2035474364 @default.
- W2897518440 cites W2036188801 @default.
- W2897518440 cites W2038533031 @default.
- W2897518440 cites W2041703347 @default.
- W2897518440 cites W2042271183 @default.
- W2897518440 cites W2045408446 @default.
- W2897518440 cites W2045539935 @default.
- W2897518440 cites W2045603426 @default.
- W2897518440 cites W2046002234 @default.
- W2897518440 cites W2046793259 @default.
- W2897518440 cites W2047763566 @default.
- W2897518440 cites W2051913120 @default.
- W2897518440 cites W2052515472 @default.
- W2897518440 cites W2052817467 @default.
- W2897518440 cites W2053293487 @default.
- W2897518440 cites W2059318013 @default.
- W2897518440 cites W2060595627 @default.
- W2897518440 cites W2062325702 @default.
- W2897518440 cites W2064705261 @default.
- W2897518440 cites W2066738380 @default.
- W2897518440 cites W2069546346 @default.
- W2897518440 cites W2071984833 @default.
- W2897518440 cites W2073584193 @default.
- W2897518440 cites W2080363338 @default.
- W2897518440 cites W2080420789 @default.
- W2897518440 cites W2083613729 @default.
- W2897518440 cites W2084424530 @default.
- W2897518440 cites W2086101311 @default.
- W2897518440 cites W2088380202 @default.
- W2897518440 cites W2094166458 @default.
- W2897518440 cites W2095565096 @default.
- W2897518440 cites W2099636172 @default.
- W2897518440 cites W2102328887 @default.
- W2897518440 cites W2108520490 @default.
- W2897518440 cites W2108613362 @default.
- W2897518440 cites W2111099236 @default.
- W2897518440 cites W2112968886 @default.
- W2897518440 cites W2113928427 @default.
- W2897518440 cites W2115030683 @default.
- W2897518440 cites W2115569719 @default.
- W2897518440 cites W2121049053 @default.
- W2897518440 cites W2127331245 @default.
- W2897518440 cites W2127384841 @default.
- W2897518440 cites W2129013527 @default.
- W2897518440 cites W2129183958 @default.
- W2897518440 cites W2129624255 @default.