Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897519076> ?p ?o ?g. }
- W2897519076 endingPage "62" @default.
- W2897519076 startingPage "54" @default.
- W2897519076 abstract "Severe burns can induce a hypercoagulable state which is not depicted in conventional coagulation assays. The thrombin generation assay allows global assessment of coagulation and can identify hypercoagulability. We report changes in thrombin generation in patients after severe burn injury.We measured TGA, rotational thrombelastometry and conventional assays in 20 consecutive patients with a total body surface area burned of >20% over a 2-week period: the day after burn trauma (A), the morning after surgical excision of burn wounds (B) and on post-admission days 7 (C) and 14 (D).Thrombin generation assay showed a procoagulatory state: there was an increase in the velocity of thrombin generation (increase in time to peak of +13%, increase in velocity index of +22%), and peak amount of thrombin (+25%) between days A and B. All parameters reached their highest levels on day C and returned towards normal on day D. Rotational thrombelastometry showed a hypercoagulable state with an increase in clot firmness and alpha angle. Conventional coagulation tests remained within reference values.In the first two weeks following burn, both the thrombin generation assay and rotational thrombelastometry show a hypercoagulable state, while conventional coagulation tests remain normal." @default.
- W2897519076 created "2018-10-26" @default.
- W2897519076 creator A5003800603 @default.
- W2897519076 creator A5011284365 @default.
- W2897519076 creator A5037945351 @default.
- W2897519076 creator A5065781341 @default.
- W2897519076 creator A5067124119 @default.
- W2897519076 creator A5071805086 @default.
- W2897519076 date "2019-02-01" @default.
- W2897519076 modified "2023-10-16" @default.
- W2897519076 title "Thrombin generation in patients with severe thermal injury" @default.
- W2897519076 cites W1975554781 @default.
- W2897519076 cites W1981682528 @default.
- W2897519076 cites W1981757126 @default.
- W2897519076 cites W1990763351 @default.
- W2897519076 cites W1993340951 @default.
- W2897519076 cites W1999196479 @default.
- W2897519076 cites W2007449934 @default.
- W2897519076 cites W2018813536 @default.
- W2897519076 cites W2032524450 @default.
- W2897519076 cites W2035144305 @default.
- W2897519076 cites W2040865519 @default.
- W2897519076 cites W2041332362 @default.
- W2897519076 cites W2042714901 @default.
- W2897519076 cites W2063215578 @default.
- W2897519076 cites W2066746471 @default.
- W2897519076 cites W2092528387 @default.
- W2897519076 cites W2095982855 @default.
- W2897519076 cites W2115233179 @default.
- W2897519076 cites W2128714925 @default.
- W2897519076 cites W2128916601 @default.
- W2897519076 cites W2163497519 @default.
- W2897519076 cites W2163723603 @default.
- W2897519076 cites W2166018647 @default.
- W2897519076 cites W2166281502 @default.
- W2897519076 cites W2171345242 @default.
- W2897519076 cites W2185336413 @default.
- W2897519076 cites W2261607489 @default.
- W2897519076 cites W2263190477 @default.
- W2897519076 cites W2293439019 @default.
- W2897519076 cites W2523258872 @default.
- W2897519076 cites W2603362583 @default.
- W2897519076 cites W2613891180 @default.
- W2897519076 cites W2620318225 @default.
- W2897519076 cites W4230938211 @default.
- W2897519076 cites W639024921 @default.
- W2897519076 doi "https://doi.org/10.1016/j.burns.2018.09.020" @default.
- W2897519076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30327230" @default.
- W2897519076 hasPublicationYear "2019" @default.
- W2897519076 type Work @default.
- W2897519076 sameAs 2897519076 @default.
- W2897519076 citedByCount "14" @default.
- W2897519076 countsByYear W28975190762019 @default.
- W2897519076 countsByYear W28975190762020 @default.
- W2897519076 countsByYear W28975190762021 @default.
- W2897519076 countsByYear W28975190762022 @default.
- W2897519076 countsByYear W28975190762023 @default.
- W2897519076 crossrefType "journal-article" @default.
- W2897519076 hasAuthorship W2897519076A5003800603 @default.
- W2897519076 hasAuthorship W2897519076A5011284365 @default.
- W2897519076 hasAuthorship W2897519076A5037945351 @default.
- W2897519076 hasAuthorship W2897519076A5065781341 @default.
- W2897519076 hasAuthorship W2897519076A5067124119 @default.
- W2897519076 hasAuthorship W2897519076A5071805086 @default.
- W2897519076 hasConcept C126322002 @default.
- W2897519076 hasConcept C141071460 @default.
- W2897519076 hasConcept C19720800 @default.
- W2897519076 hasConcept C2776782833 @default.
- W2897519076 hasConcept C2777292125 @default.
- W2897519076 hasConcept C2778261982 @default.
- W2897519076 hasConcept C2778382381 @default.
- W2897519076 hasConcept C2779936836 @default.
- W2897519076 hasConcept C2780077467 @default.
- W2897519076 hasConcept C3018972837 @default.
- W2897519076 hasConcept C42219234 @default.
- W2897519076 hasConcept C71924100 @default.
- W2897519076 hasConcept C89560881 @default.
- W2897519076 hasConceptScore W2897519076C126322002 @default.
- W2897519076 hasConceptScore W2897519076C141071460 @default.
- W2897519076 hasConceptScore W2897519076C19720800 @default.
- W2897519076 hasConceptScore W2897519076C2776782833 @default.
- W2897519076 hasConceptScore W2897519076C2777292125 @default.
- W2897519076 hasConceptScore W2897519076C2778261982 @default.
- W2897519076 hasConceptScore W2897519076C2778382381 @default.
- W2897519076 hasConceptScore W2897519076C2779936836 @default.
- W2897519076 hasConceptScore W2897519076C2780077467 @default.
- W2897519076 hasConceptScore W2897519076C3018972837 @default.
- W2897519076 hasConceptScore W2897519076C42219234 @default.
- W2897519076 hasConceptScore W2897519076C71924100 @default.
- W2897519076 hasConceptScore W2897519076C89560881 @default.
- W2897519076 hasIssue "1" @default.
- W2897519076 hasLocation W28975190761 @default.
- W2897519076 hasLocation W28975190762 @default.
- W2897519076 hasOpenAccess W2897519076 @default.
- W2897519076 hasPrimaryLocation W28975190761 @default.
- W2897519076 hasRelatedWork W1993476113 @default.
- W2897519076 hasRelatedWork W2023594284 @default.
- W2897519076 hasRelatedWork W2026214634 @default.