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- W2897534849 abstract "Between 10 and 15% of Parkinson disease (PD) cases can be traced to a genetically identified causative mutation which currently number over 40. This enables the study of both at risk populations for future development of PD and a unique sub-group of genetically determined patient population. Structural and functional magnetic imaging has the potential of assisting diagnosis, early detection and disease progression as it is relatively cheap and easy to implement. However, the large variety of imaging options and different analytical approaches hamper the pursuit of a unified imaging biomarker. This chapter details the current imaging options and summarizes the findings among both genetically determined patients with PD and their non-manifesting first degree relatives, speculating on possible compensational mechanisms while mapping future directions in order to better utilize MRI in the research of genetic PD." @default.
- W2897534849 created "2018-10-26" @default.
- W2897534849 creator A5052108043 @default.
- W2897534849 date "2018-01-01" @default.
- W2897534849 modified "2023-09-24" @default.
- W2897534849 title "Structural and Functional MRI in Familial Parkinson's Disease" @default.
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- W2897534849 doi "https://doi.org/10.1016/bs.irn.2018.09.005" @default.
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