FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897537454> ?p ?o ?g. }

• W2897537454 endingPage "453" @default.
• W2897537454 startingPage "447" @default.
• W2897537454 abstract "The PI3K/AKT/mTOR pathway is known to play an important role in regulating angiogenesis both in normal and breast cancer (BC) tissues. PIK3CA amplification was reported in various malignancies, including approximately 10% of BC cases. The aim of this study was to identify the frequency of PIK3CA amplification in Iranian female patients suffering from BC. Additionally, possible association between PIK3CA amplification and P110α expression with microvascular density (MVD) was examined.DNA samples were extracted from paraffin embedded tumor tissue blocks and copy number changes were evaluated by MLPA Technique. The results were analyzed by coffalyzer software. The tissue expression of P110α and CD34 was assessed using immunohistochemistry.Ten out of 40 samples (17.5%) showed amplification in PIK3CA gene and 22 out of 40 samples (55%) showed overexpression in P110α. For CD34, from 40 samples, 20 (50%), 15 (37.5%) and 5 (12.5%) had scores 1+, 2+ and 3+, respectively.No significant association was detected between gain of PIK3CA copy number and P110α or CD34 tissue expression." @default.
• W2897537454 created "2018-10-26" @default.
• W2897537454 creator A5011886514 @default.
• W2897537454 creator A5025485957 @default.
• W2897537454 creator A5025755468 @default.
• W2897537454 creator A5029760589 @default.
• W2897537454 creator A5059041074 @default.
• W2897537454 creator A5064758964 @default.
• W2897537454 creator A5065802022 @default.
• W2897537454 creator A5065832372 @default.
• W2897537454 creator A5070212840 @default.
• W2897537454 creator A5088839183 @default.
• W2897537454 date "2018-01-01" @default.
• W2897537454 modified "2023-09-26" @default.
• W2897537454 title "Relationship Between PIK3CA Amplification and P110α and CD34 Tissue Expression as Angiogenesis Markers in Iranian Women with Sporadic Breast Cancer." @default.
• W2897537454 cites W1545893705 @default.
• W2897537454 cites W1574678914 @default.
• W2897537454 cites W1594020010 @default.
• W2897537454 cites W1605218581 @default.
• W2897537454 cites W1826483772 @default.
• W2897537454 cites W1918395140 @default.
• W2897537454 cites W1963981090 @default.
• W2897537454 cites W1971843650 @default.
• W2897537454 cites W1972774425 @default.
• W2897537454 cites W1977267072 @default.
• W2897537454 cites W1978139448 @default.
• W2897537454 cites W1981711832 @default.
• W2897537454 cites W2014087704 @default.
• W2897537454 cites W2020830322 @default.
• W2897537454 cites W2032129723 @default.
• W2897537454 cites W2042949684 @default.
• W2897537454 cites W2080309793 @default.
• W2897537454 cites W2100608628 @default.
• W2897537454 cites W2120943945 @default.
• W2897537454 cites W2126569401 @default.
• W2897537454 cites W2134945055 @default.
• W2897537454 cites W2137455932 @default.
• W2897537454 cites W2137953043 @default.
• W2897537454 cites W2147652669 @default.
• W2897537454 cites W2152317073 @default.
• W2897537454 cites W2159791307 @default.
• W2897537454 cites W2282445370 @default.
• W2897537454 cites W2314755674 @default.
• W2897537454 cites W2412432167 @default.
• W2897537454 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6358562" @default.
• W2897537454 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30774684" @default.
• W2897537454 hasPublicationYear "2018" @default.
• W2897537454 type Work @default.
• W2897537454 sameAs 2897537454 @default.
• W2897537454 citedByCount "1" @default.
• W2897537454 countsByYear W28975374542022 @default.
• W2897537454 crossrefType "journal-article" @default.
• W2897537454 hasAuthorship W2897537454A5011886514 @default.
• W2897537454 hasAuthorship W2897537454A5025485957 @default.
• W2897537454 hasAuthorship W2897537454A5025755468 @default.
• W2897537454 hasAuthorship W2897537454A5029760589 @default.
• W2897537454 hasAuthorship W2897537454A5059041074 @default.
• W2897537454 hasAuthorship W2897537454A5064758964 @default.
• W2897537454 hasAuthorship W2897537454A5065802022 @default.
• W2897537454 hasAuthorship W2897537454A5065832372 @default.
• W2897537454 hasAuthorship W2897537454A5070212840 @default.
• W2897537454 hasAuthorship W2897537454A5088839183 @default.
• W2897537454 hasConcept C10205521 @default.
• W2897537454 hasConcept C104317684 @default.
• W2897537454 hasConcept C121608353 @default.
• W2897537454 hasConcept C126322002 @default.
• W2897537454 hasConcept C142724271 @default.
• W2897537454 hasConcept C143998085 @default.
• W2897537454 hasConcept C204232928 @default.
• W2897537454 hasConcept C2780394083 @default.
• W2897537454 hasConcept C28328180 @default.
• W2897537454 hasConcept C502942594 @default.
• W2897537454 hasConcept C530470458 @default.
• W2897537454 hasConcept C54355233 @default.
• W2897537454 hasConcept C71924100 @default.
• W2897537454 hasConcept C7602840 @default.
• W2897537454 hasConcept C86803240 @default.
• W2897537454 hasConceptScore W2897537454C10205521 @default.
• W2897537454 hasConceptScore W2897537454C104317684 @default.
• W2897537454 hasConceptScore W2897537454C121608353 @default.
• W2897537454 hasConceptScore W2897537454C126322002 @default.
• W2897537454 hasConceptScore W2897537454C142724271 @default.
• W2897537454 hasConceptScore W2897537454C143998085 @default.
• W2897537454 hasConceptScore W2897537454C204232928 @default.
• W2897537454 hasConceptScore W2897537454C2780394083 @default.
• W2897537454 hasConceptScore W2897537454C28328180 @default.
• W2897537454 hasConceptScore W2897537454C502942594 @default.
• W2897537454 hasConceptScore W2897537454C530470458 @default.
• W2897537454 hasConceptScore W2897537454C54355233 @default.
• W2897537454 hasConceptScore W2897537454C71924100 @default.
• W2897537454 hasConceptScore W2897537454C7602840 @default.
• W2897537454 hasConceptScore W2897537454C86803240 @default.
• W2897537454 hasIssue "4" @default.
• W2897537454 hasLocation W28975374541 @default.
• W2897537454 hasOpenAccess W2897537454 @default.
• W2897537454 hasPrimaryLocation W28975374541 @default.
• W2897537454 hasVolume "13" @default.
• W2897537454 isParatext "false" @default.

• next