Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897556142> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2897556142 endingPage "553" @default.
- W2897556142 startingPage "549" @default.
- W2897556142 abstract "Objective: The aim of this study was to evaluate the use of novel estradiol metered-dose transdermal spray (EMDTS) in the treatment of acute climacteric syndrome.Methods: A multicenter open-label trial was conducted with a 24-week intervention. EMDTS 1.53 mg was given to symptomatic menopausal women. The Menopause Rating Scale (MRS) was used to assess the climacteric syndrome severity. The Friedman non-parametric test and a post-hoc test with Bonferroni correction were used for statistical evaluation.Results: A total of 132 women were enrolled in 20 centers, of whom 123 (93.2%) completed the study. The average age of patients was 53.8 years (37–65 years). The study was discontinued by 6.8% of women. The patients were checked at the beginning of the study, and after 12 and 24 weeks. There was a statistically significant drop (p < 0.001) in MRS values both after 12 and 24 weeks of therapy. The average MRS values improved by 66.2% between the first and the third visits. The most significant improvement was manifested in patients with initial moderate climacteric syndrome (70.9%).Conclusion: This study confirms that application of EMDTS offers a novel treatment option for climacteric symptoms." @default.
- W2897556142 created "2018-10-26" @default.
- W2897556142 creator A5023490191 @default.
- W2897556142 creator A5030701957 @default.
- W2897556142 creator A5045163476 @default.
- W2897556142 date "2018-10-08" @default.
- W2897556142 modified "2023-10-18" @default.
- W2897556142 title "The use of estradiol metered-dose transdermal spray in clinical practice" @default.
- W2897556142 cites W1779686469 @default.
- W2897556142 cites W1966638782 @default.
- W2897556142 cites W2003292227 @default.
- W2897556142 cites W2015424404 @default.
- W2897556142 cites W2022361277 @default.
- W2897556142 cites W2026845568 @default.
- W2897556142 cites W2054122547 @default.
- W2897556142 cites W2054234406 @default.
- W2897556142 cites W2060921815 @default.
- W2897556142 cites W2081278964 @default.
- W2897556142 cites W2088142700 @default.
- W2897556142 cites W2118379947 @default.
- W2897556142 cites W2131992106 @default.
- W2897556142 cites W2137194674 @default.
- W2897556142 cites W2411255790 @default.
- W2897556142 cites W4251459845 @default.
- W2897556142 doi "https://doi.org/10.1080/13697137.2018.1504916" @default.
- W2897556142 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30296172" @default.
- W2897556142 hasPublicationYear "2018" @default.
- W2897556142 type Work @default.
- W2897556142 sameAs 2897556142 @default.
- W2897556142 citedByCount "4" @default.
- W2897556142 countsByYear W28975561422019 @default.
- W2897556142 countsByYear W28975561422020 @default.
- W2897556142 countsByYear W28975561422023 @default.
- W2897556142 crossrefType "journal-article" @default.
- W2897556142 hasAuthorship W2897556142A5023490191 @default.
- W2897556142 hasAuthorship W2897556142A5030701957 @default.
- W2897556142 hasAuthorship W2897556142A5045163476 @default.
- W2897556142 hasConcept C105795698 @default.
- W2897556142 hasConcept C126322002 @default.
- W2897556142 hasConcept C127808970 @default.
- W2897556142 hasConcept C1862650 @default.
- W2897556142 hasConcept C198454886 @default.
- W2897556142 hasConcept C205679159 @default.
- W2897556142 hasConcept C2775842315 @default.
- W2897556142 hasConcept C2778562196 @default.
- W2897556142 hasConcept C33923547 @default.
- W2897556142 hasConcept C535046627 @default.
- W2897556142 hasConcept C65409693 @default.
- W2897556142 hasConcept C67761136 @default.
- W2897556142 hasConcept C71924100 @default.
- W2897556142 hasConcept C98274493 @default.
- W2897556142 hasConceptScore W2897556142C105795698 @default.
- W2897556142 hasConceptScore W2897556142C126322002 @default.
- W2897556142 hasConceptScore W2897556142C127808970 @default.
- W2897556142 hasConceptScore W2897556142C1862650 @default.
- W2897556142 hasConceptScore W2897556142C198454886 @default.
- W2897556142 hasConceptScore W2897556142C205679159 @default.
- W2897556142 hasConceptScore W2897556142C2775842315 @default.
- W2897556142 hasConceptScore W2897556142C2778562196 @default.
- W2897556142 hasConceptScore W2897556142C33923547 @default.
- W2897556142 hasConceptScore W2897556142C535046627 @default.
- W2897556142 hasConceptScore W2897556142C65409693 @default.
- W2897556142 hasConceptScore W2897556142C67761136 @default.
- W2897556142 hasConceptScore W2897556142C71924100 @default.
- W2897556142 hasConceptScore W2897556142C98274493 @default.
- W2897556142 hasIssue "6" @default.
- W2897556142 hasLocation W28975561421 @default.
- W2897556142 hasLocation W28975561422 @default.
- W2897556142 hasOpenAccess W2897556142 @default.
- W2897556142 hasPrimaryLocation W28975561421 @default.
- W2897556142 hasRelatedWork W1948357850 @default.
- W2897556142 hasRelatedWork W2023928009 @default.
- W2897556142 hasRelatedWork W2040159435 @default.
- W2897556142 hasRelatedWork W2056151646 @default.
- W2897556142 hasRelatedWork W2143031715 @default.
- W2897556142 hasRelatedWork W2421789324 @default.
- W2897556142 hasRelatedWork W2511316169 @default.
- W2897556142 hasRelatedWork W2772489491 @default.
- W2897556142 hasRelatedWork W2897556142 @default.
- W2897556142 hasRelatedWork W799332803 @default.
- W2897556142 hasVolume "21" @default.
- W2897556142 isParatext "false" @default.
- W2897556142 isRetracted "false" @default.
- W2897556142 magId "2897556142" @default.
- W2897556142 workType "article" @default.