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- W2897557944 abstract "To investigate the outcome of fetuses affected by congenital heart disease (CHD) detected prenatally in a tertiary centre (Hung Vuong Maternal Hospital) in Vietnam. A retrospective study conducted between January and December 2017. A database search was used to identify fetuses with a prenatal ultrasound diagnosis of CHD. Short-term outcomes (termination of pregnancy (ToP), chromosome abnormalities, intrauterine fetal or infant death were compared for gestational at diagnosis and association with other structures or chromosomal abnormalities. 63 (17.6%) of fetuses that had a prenatal diagnosis of a major structural defect had CHD. In 36 (57%) cases CHD was isolated whilst the remaining 27 (43%) of cases had at least one associated structural anomaly. Diagnosis was made earlier (mean 19.3 versus 22.6 weeks; p=0.02) when there were multiple structural abnormalities. Women were more likely to have a ToP if there were multiple structural abnormalities (88% versus 47% respectively (p=0.001)). Fetuses with multiple structural abnormalities were also more likely to have a chromosomal abnormality (38% versus 33%), to die in utero (33% versus 10%) or die in infancy (33% versus 26%) than fetuses with isolated CHD, although none of these differences was statistically significant. The overall survival rates were 33% and 4% for fetuses with isolated or multiple structural defects (p=0.04). Outcomes of fetuses with congenital heart disease in our centre are poor even if the abnormality is isolated. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
- W2897557944 created "2018-10-26" @default.
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- W2897557944 date "2018-10-01" @default.
- W2897557944 modified "2023-10-18" @default.
- W2897557944 title "EP10.04: Outcomes of fetuses with prenatally diagnosed congenital heart disease in a tertiary centre in South Vietnam" @default.
- W2897557944 doi "https://doi.org/10.1002/uog.19933" @default.
- W2897557944 hasPublicationYear "2018" @default.
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