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• W2897577634 endingPage "1933" @default.
• W2897577634 startingPage "1921" @default.
• W2897577634 abstract "Giardia is the commonest parasitic diarrheal pathogen affecting humans and a frequent cause of waterborne/foodborne parasitic diseases worldwide. Prevalence of giardiasis is higher in children, living in poor, low hygiene settings in developing countries, and in travelers returning from highly endemic areas. The clinical picture of giardiasis is heterogeneous, with high variability in severity of clinical disease. It can become chronic or be followed by post-infectious sequelae. An alarming increase in cases refractory to the conventional treatment with nitroimidazoles (ie, metronidazole) has been reported in low prevalence settings, such as European Union countries, especially in patients returning from Asia. In view of its relevance, we aim in this review to recapitulate present clinical knowledge about Giardia, with a special focus on the challenge of treatment-refractory giardiasis. We propose a working definition of clinically drug-resistant giardiasis, summarize knowledge regarding resistance mechanisms, and discuss its clinical management according to research-based evidence and medical practice. Advances in development and identification of novel drugs and potential non-pharmacological alternatives are also reviewed with the overall aim to define knowledge gaps and suggest future directions for research." @default.
• W2897577634 created "2018-10-26" @default.
• W2897577634 creator A5038224954 @default.
• W2897577634 creator A5058214741 @default.
• W2897577634 date "2018-10-01" @default.
• W2897577634 modified "2023-10-16" @default.
• W2897577634 title "Treatment-refractory giardiasis: challenges and solutions" @default.
• W2897577634 cites W1528163728 @default.
• W2897577634 cites W1563007037 @default.
• W2897577634 cites W1566729005 @default.
• W2897577634 cites W1590526322 @default.
• W2897577634 cites W1600448050 @default.
• W2897577634 cites W1637667857 @default.
• W2897577634 cites W1772697273 @default.
• W2897577634 cites W1910724265 @default.
• W2897577634 cites W1930144865 @default.
• W2897577634 cites W1963755983 @default.
• W2897577634 cites W1963896084 @default.
• W2897577634 cites W1964027206 @default.
• W2897577634 cites W1965111317 @default.
• W2897577634 cites W1968710639 @default.
• W2897577634 cites W1969558402 @default.
• W2897577634 cites W1984910114 @default.
• W2897577634 cites W1987192533 @default.
• W2897577634 cites W1988823573 @default.
• W2897577634 cites W1991858217 @default.
• W2897577634 cites W2000481275 @default.
• W2897577634 cites W2004887492 @default.
• W2897577634 cites W2008738643 @default.
• W2897577634 cites W2011509680 @default.
• W2897577634 cites W2016243559 @default.
• W2897577634 cites W2018926532 @default.
• W2897577634 cites W2029054876 @default.
• W2897577634 cites W2033704256 @default.
• W2897577634 cites W2047491588 @default.
• W2897577634 cites W2049133510 @default.
• W2897577634 cites W2049289239 @default.
• W2897577634 cites W2058850623 @default.
• W2897577634 cites W2069976801 @default.
• W2897577634 cites W2072115966 @default.
• W2897577634 cites W2074730909 @default.
• W2897577634 cites W2078727354 @default.
• W2897577634 cites W2081593786 @default.
• W2897577634 cites W2086432736 @default.
• W2897577634 cites W2087386008 @default.
• W2897577634 cites W2089503312 @default.
• W2897577634 cites W2093753186 @default.
• W2897577634 cites W2097357567 @default.
• W2897577634 cites W2097842505 @default.
• W2897577634 cites W2100085650 @default.
• W2897577634 cites W2103036542 @default.
• W2897577634 cites W2103580630 @default.
• W2897577634 cites W2106847587 @default.
• W2897577634 cites W2108375849 @default.
• W2897577634 cites W2114523002 @default.
• W2897577634 cites W2116905112 @default.
• W2897577634 cites W2123047959 @default.
• W2897577634 cites W2124318306 @default.
• W2897577634 cites W2124964277 @default.
• W2897577634 cites W2133153279 @default.
• W2897577634 cites W2135703429 @default.
• W2897577634 cites W2139425464 @default.
• W2897577634 cites W2139589162 @default.
• W2897577634 cites W2139782936 @default.
• W2897577634 cites W2141688115 @default.
• W2897577634 cites W2152238692 @default.
• W2897577634 cites W2152477480 @default.
• W2897577634 cites W2152977880 @default.
• W2897577634 cites W2155730649 @default.
• W2897577634 cites W2157726173 @default.
• W2897577634 cites W2158046792 @default.
• W2897577634 cites W2158676715 @default.
• W2897577634 cites W2160454557 @default.
• W2897577634 cites W2162530439 @default.
• W2897577634 cites W2167317062 @default.
• W2897577634 cites W2184405267 @default.
• W2897577634 cites W2240105222 @default.
• W2897577634 cites W2332348819 @default.
• W2897577634 cites W2348780213 @default.
• W2897577634 cites W2412670509 @default.
• W2897577634 cites W2425298692 @default.
• W2897577634 cites W2460767197 @default.
• W2897577634 cites W2487591841 @default.
• W2897577634 cites W2507767803 @default.
• W2897577634 cites W2524198762 @default.
• W2897577634 cites W2553839383 @default.
• W2897577634 cites W2556999435 @default.
• W2897577634 cites W2580982351 @default.
• W2897577634 cites W2586936592 @default.
• W2897577634 cites W2588331788 @default.
• W2897577634 cites W2588881920 @default.
• W2897577634 cites W2590003621 @default.
• W2897577634 cites W2590516092 @default.
• W2897577634 cites W2595952830 @default.
• W2897577634 cites W2601341455 @default.
• W2897577634 cites W2605700745 @default.
• W2897577634 cites W2606004738 @default.
• W2897577634 cites W2608119303 @default.

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