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- W2897577709 abstract "The study aimed at genetic analysis of amniocentesis (karyotypes) for prenatal diagnosis. Methodology: this is a retrospective study among pregnant women indicated for amniocentesis and consent to the study. 11,463 cases were included to the study during 5 years’ period from 2012 to 2016. Results: The rate of successful karyotyping was 99.9%, 10 cases (0.1%) were failure to obtain karyotype. The complication of amniocentesis was miscarriage (0.05%). Acceptance rates for amniocentesis in total number of deliveries were 10.7%, and indications for amniocentesis were mainly high-risk pregnancy such as advanced maternal age, increased nuchal transluciency and abnormalities were observed by ultrasonography. Chromosomal abnormalities are 6.7%, popular conditions were found including trisomy 21(40.6%), trisomy 18 (13.8%), trisomy 13 (2.1%), 45, XO (1.9%). Conclusion: Obtaining fetal fraction by amniocentesis is completely feasible, has great efficacy, safety and helps making decision on the fate of pregnancy." @default.
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- W2897577709 date "2018-01-01" @default.
- W2897577709 modified "2023-10-15" @default.
- W2897577709 title "Genetic Analysis for Prenatal Diagnosis via Amniocentesis at Vietnam National Hospital of Obstetrics and Gyneacology from 2012 to 2016" @default.
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