Matches in SemOpenAlex for { <https://semopenalex.org/work/W2897589308> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2897589308 endingPage "125" @default.
- W2897589308 startingPage "124" @default.
- W2897589308 abstract "Fetal middle cerebral artery Doppler (MCA) is recognised as a marker of hypoxia in fetal growth restriction with a reduction in impedance classically described as the “brain sparing effect”. We report elsewhere a relationship between maternal hemodynamic function and both uterine and umbilical impedance, and sought to investigate whether fetal middle cerebral artery Doppler was related to maternal cardiac output (CO) and peripheral vascular resistance (PVR) in healthy and complicated pregnancy. In this prospective study, women between 24-40 weeks gestation were recruited into 4 groups – pre-eclampsia only (PE), fetal growth restriction only (FGR), fetal growth restriction with pre-eclampsia (PE+FGR) and healthy pregnancies acting as controls. PE was defined as maternal blood pressure at diagnosis of > 140/90 mmHg and urine protein creatinine ratio of > 30. FGR was defined as fetal abdominal circumference < 10th percentile and umbilical Doppler PI > 95th centile on ultrasound scan. Those with pre-existing chronic hypertension or fetal anomaly were excluded. Maternal CO was assessed with Innocor, an inert gas non-rebreathing technique in the upright position and PVR derived. Fetal MCA PI was recorded and all observations were Z scored to account for gestation effect. Polynomial regression analyses were undertaken to determine association. There were no associations identified between fetal middle cerebral artery PI and maternal cardiac output (p=0.51) or peripheral vascular resistance (p=0.14). In pregnancies with pathological outcome and healthy pregnancies, no correlation is observed between maternal hemodynamic parameters and fetal middle cerebral artery Doppler indices. This indicates that, in contrast to uterine and umbilical artery indices, low maternal cardiac output does not obviously translate to fetal hypoxemia as evidenced by brainsparing. Supporting information can be found in the online version of this abstract Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
- W2897589308 created "2018-10-26" @default.
- W2897589308 creator A5018879693 @default.
- W2897589308 creator A5019042733 @default.
- W2897589308 creator A5022889845 @default.
- W2897589308 creator A5041039701 @default.
- W2897589308 creator A5056272138 @default.
- W2897589308 date "2018-10-01" @default.
- W2897589308 modified "2023-09-24" @default.
- W2897589308 title "OP19.09: Fetal middle cerebral artery Doppler impedance is not related to maternal hemodynamic function" @default.
- W2897589308 doi "https://doi.org/10.1002/uog.19573" @default.
- W2897589308 hasPublicationYear "2018" @default.
- W2897589308 type Work @default.
- W2897589308 sameAs 2897589308 @default.
- W2897589308 citedByCount "0" @default.
- W2897589308 crossrefType "journal-article" @default.
- W2897589308 hasAuthorship W2897589308A5018879693 @default.
- W2897589308 hasAuthorship W2897589308A5019042733 @default.
- W2897589308 hasAuthorship W2897589308A5022889845 @default.
- W2897589308 hasAuthorship W2897589308A5041039701 @default.
- W2897589308 hasAuthorship W2897589308A5056272138 @default.
- W2897589308 hasBestOaLocation W28975893081 @default.
- W2897589308 hasConcept C126322002 @default.
- W2897589308 hasConcept C131872663 @default.
- W2897589308 hasConcept C164705383 @default.
- W2897589308 hasConcept C172680121 @default.
- W2897589308 hasConcept C178853913 @default.
- W2897589308 hasConcept C2775841333 @default.
- W2897589308 hasConcept C2776046940 @default.
- W2897589308 hasConcept C2778780700 @default.
- W2897589308 hasConcept C2778964498 @default.
- W2897589308 hasConcept C2779234561 @default.
- W2897589308 hasConcept C2781207646 @default.
- W2897589308 hasConcept C2781276381 @default.
- W2897589308 hasConcept C46973012 @default.
- W2897589308 hasConcept C541997718 @default.
- W2897589308 hasConcept C54355233 @default.
- W2897589308 hasConcept C58245268 @default.
- W2897589308 hasConcept C71924100 @default.
- W2897589308 hasConcept C86803240 @default.
- W2897589308 hasConceptScore W2897589308C126322002 @default.
- W2897589308 hasConceptScore W2897589308C131872663 @default.
- W2897589308 hasConceptScore W2897589308C164705383 @default.
- W2897589308 hasConceptScore W2897589308C172680121 @default.
- W2897589308 hasConceptScore W2897589308C178853913 @default.
- W2897589308 hasConceptScore W2897589308C2775841333 @default.
- W2897589308 hasConceptScore W2897589308C2776046940 @default.
- W2897589308 hasConceptScore W2897589308C2778780700 @default.
- W2897589308 hasConceptScore W2897589308C2778964498 @default.
- W2897589308 hasConceptScore W2897589308C2779234561 @default.
- W2897589308 hasConceptScore W2897589308C2781207646 @default.
- W2897589308 hasConceptScore W2897589308C2781276381 @default.
- W2897589308 hasConceptScore W2897589308C46973012 @default.
- W2897589308 hasConceptScore W2897589308C541997718 @default.
- W2897589308 hasConceptScore W2897589308C54355233 @default.
- W2897589308 hasConceptScore W2897589308C58245268 @default.
- W2897589308 hasConceptScore W2897589308C71924100 @default.
- W2897589308 hasConceptScore W2897589308C86803240 @default.
- W2897589308 hasIssue "S1" @default.
- W2897589308 hasLocation W28975893081 @default.
- W2897589308 hasOpenAccess W2897589308 @default.
- W2897589308 hasPrimaryLocation W28975893081 @default.
- W2897589308 hasRelatedWork W1989415021 @default.
- W2897589308 hasRelatedWork W1990912731 @default.
- W2897589308 hasRelatedWork W2029935835 @default.
- W2897589308 hasRelatedWork W2065472998 @default.
- W2897589308 hasRelatedWork W2068183540 @default.
- W2897589308 hasRelatedWork W2081019966 @default.
- W2897589308 hasRelatedWork W2084104558 @default.
- W2897589308 hasRelatedWork W3048770518 @default.
- W2897589308 hasRelatedWork W4308249204 @default.
- W2897589308 hasRelatedWork W1984085762 @default.
- W2897589308 hasVolume "52" @default.
- W2897589308 isParatext "false" @default.
- W2897589308 isRetracted "false" @default.
- W2897589308 magId "2897589308" @default.
- W2897589308 workType "article" @default.